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 June 29, 2007
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Designer Enzyme to Fight HIV Shows Promise
Scientists in Germany have constructed a custom enzyme that reverses the process by which HIV inserts its genetic material into a CD4 cell's DNA, suggesting that treatment with similar enzymes could potentially rid infected cells of the virus.
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Polyalkylimide Injections Improve HIV Lipoatrophy
Using a facial filler such as polyalkylimide gel (PAIG) injections can correct the antiretroviral-associated facial lipoatrophy that can be quite severe in HIV-infected individuals, Canadian investigators report in May 31st issue of AIDS.
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| June 28, 2007
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June 27, 2007
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Neuro Problems may Persist with Treatment
Neuropsychological deficits in HIV-infected patients persist despite
long-term highly active antiretroviral therapy (HAART), according to a
report in the June 1st Journal of Acquired Immune Deficiency Syndromes.
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HIV, PIs Don't Lead to Artery Thickening
Neither HIV infection nor the use of protease inhibitors (PIs) appear
to affect the rate of carotid artery intima media thickening (IMT)
progression, AIDS investigators report, despite the lipid abnormalities
that have been associated with PI therapy.
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June 26, 2007
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Treatment Improves Survival Among IDUs
Survival among HIV-infected intravenous drug users (IDUs) has improved dramatically since the introduction of combination antiretroviral therapy, with survival rates similar to HIV-negative IDUs.
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| June 25, 2007
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June 22, 2007
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Drug-Resistant HIV in Semen Stirs Concerns
Drug-resistant HIV can remain detectable in the male genital tract for an extended period of time, and potentially prolong the risk to sexual partners, according to a study published in the August 1 issue of the Journal of Infectious Disease.
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June 21, 2007
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Hep B and HIV Baraclude Users Beware
Treating hepatitis B patients with the drug Baraclude® (entecavir) can cause those who are also infected with HIV to become resistant to two vital HIV drugs, according to a new report in the New England Journal of Medicine.
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Panacos' Bevirimat Back on Track
Panacos Pharmaceuticals reports that it is back on track with the development of its maturation inhibitor bevirimat (PA-457), after hitting a dosing snag reported in December 2006.
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| June 20, 2007
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June 19, 2007
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Reyataz May Cause Kidney Stones
The FDA has received 30 reports of kidney stones among HIV-positive patients being treated with Reyataz, prompting the company to update the drug's package insert.
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June 15, 2007
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Several Factors Raise Women's Bone Loss Risk
Decreased bone mineral density (BMD) is both highly prevalent and severe among underweight women with HIV and is associated with other factors like menstrual irregularities, reduced testosterone levels, lower lean body mass, and white race.
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| June 14, 2007
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June 12, 2007
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Non-Nuke Shows Early Promise as Microbicide
Macaques given an investigational non-nucleoside reverse transcriptase
inhibitor (NNRTI) gel called UC781 in repeated vaginal and rectal
applications exhibited no evidence of systemic absorption, researchers
report.
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| June 11, 2007
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| June 08, 2007
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| June 07, 2007
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June 06, 2007
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New Drugs Possible from Discovered HIV Transport System
Likening HIV to “hobos on a train,” researchers at Johns Hopkins University School of Medicine have found that the virus uses a pre-existing transport system to leave one infected CD4 cell and move on to infect news ones.
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June 05, 2007
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Early Treatment may have CD4 Advantage
The chances of achieving and maintaining a CD4 count of 800 or higher are best among those who start antiretroviral therapy early, according to new data from the ATHENA cohort study.
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