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Perhaps the lower test scores were a result of the drugs themselves. It is common knowledge that Sustiva users report CNS-related symptoms, which would adversely effect neuropsychological test scores. Hopefully these drugs that penetrate the CNS are not causing any permanent impairment of cognitive function. If test subjects were switched to a non-impairing medication and tested again, their scores might improve. Cognitive decline studies need long-term data, not these one-off paper generators!
Just a wild guess..Sustiva or such...ammmm are known as deep CSN drillers...
my cognitive function, memory, physical coordination and vision did NOT begin to deteriorate UNTIL i began taking the meds (HAART). my brain, muscles and eyes were all working just FINE, before i began the HAART regimen... even though my CD4 count was very low (30) & viral load high (over 100,000). yes, the medications are keeping me alive (i assume), but the negative physical side-effects of HAART were almost immediate, especially slowed thinking, poor eyesight, GI problems, and so on.
Jae
There seem to be many important issues not explored ie age, length of time living with HIV, other health issues like depression or which classes of drugs were used. Medications with superior penetration of the CSF are used to treat HIV Associated Neuropathic Disorder (HAND)with great success. Sustiva has one of the poorest penetrators of CSF.
July 8, 2009 • Sydney