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Harry, I wouldn't panic about these results. Several studies have concluded that uncontrolled HIV does have an impact on the brain. Fortunately, these studies also suggested that while a lot of people show some signs of cognitive problems, the problems are usually so minor that they don't have any meaningful impact on a person's daily living. The main point of this study is that once you start ARV treatment, it's best to stay on it consistently. There are immune-based therapies being studied right now that might allow safe breaks from treatment, but we aren't there yet.
I am concerned about these results! Did you guys know about that?? www.ncbi.nlm.nih.gov/pubmed/20450380
Of course, another way to "Protect Your Options" is not to start treatment any earlier than is necessary. Many people with higher CD4 counts live without antiretroviral treatment for many years with few or no symptoms, and minimal or no viral load, despite having HIV.
por favor pon mucha atenncion a esto plis!...
I was in one of the Vicriviroc studies with two agents. It worked extremely well for me and I was very frustrated to see this drug dropped. It had a very low side effect profile, was very easy to take, and we could have switched out the other active drug as it was causing side effect issues. While we are content now, our future will depend on a stable of better drugs with fewer side effects and lower dosages.
MineMan
No mention of gene therapy being investigated at several, UPenn and UCSF, UCSD, Matt Sharp and the good Dr. Have an excellent NEW video describing this treatment. Sponsored by Sangamo Biosciences, and CIRM. They are looking for volunteers for the therapy which is hoped could lead to a virtual if not actual cure. I suggest this video be presented on TV in SF, and a mention of the trial volunteers. Seems to be one of the best kept secrets in HIV.
January 5, 2011 • Dallas