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Table of Contents


A Model Activist

Hep Cat

The Brave Lady of Haiti

Mighty Real

Big, Bad Media Bugout

Earthwatch

PEP on the Down Low

Quick Studies

Legal Eye

On the March!

Notes on Camp

Kentucky Fried Bigots?

POZ Picks

Hollywood to HIVers: Drop Dead

Ouch!

Veggie Table

Don't Run

A Peek in the Pipeline

Ducking Resistance

Quick Study

Pharm Team

Warning!

Haartbeats

Editor's Letter

Mailbox

Teen Jeopardy

Heavy Lifting


Most Talked About

Does Undetectable Equal Uninfectious? (21)

Just Found Out? A POZ.com Guide for HIV Rookies (11)

The Blood of Christ (a powerful one-man AIDS protest) (Blog) (9)

The State of AIDS in Puerto Rico (9)

Rethinking Criminalization of HIV (8)

Life Expectancy With HIV Increases Dramatically (6)

Most Popular Lessons

The HIV Life Cycle

Herpes Simplex Virus

Human Papilloma Virus (HPV)

Shingles

Syphilis & Neurosyphilis

Treatments for Opportunistic Infections (OIs)


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May 2005


Haartbeats

by Tim Murphy

Med-news nuggets from CROI, the year's biggest AIDS confab:

FAT FOLLIES  In two 2-year studies of arm and leg fat loss (lipoatrophy), ditching a multi-nuke combo for one with only a protease inhibitor (PI) and a non-nuke modestly restored fat—and still controlled HIV. • Another study found that replacing AZT or Zerit with Ziagen or Viread let HIVers regain a bit o’ fat over a year. Zerit has long been tied to fat loss, but “AZT’s getting the heat now” for milder cases, says treatment activist Nelson Vergel.

VIRAL VANQUISHERS  Countering critics of triple-nuke combos, Combivir (AZT + 3TC) plus Viread controlled most HIVers’ viral loads for about eight months in a small French study. • A San Fran study found that taking meds only 70 percent of the time controlled viral loads in HIVers on non-nuke–based regimens, but not in those on unboosted PI-based combos (likely because non-nukes last a loooong time in your body).

BEST TESTS  Two studies endorsed the effectiveness of checking blood levels of HIVers’ HAART meds, then  adjusting doses as needed—stoking the argument for therapeutic drug monitoring (TDM) • A study of HIVer women found that 36 percent who had normal cervical Pap smears turned up with abnormal anal Paps—reminding the ladies to have doc swab back there, too.
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