December #108 : They Soothe Tootsies, Don’t They? - by Brett Moskowitz

POZ - Health, Life and HIV
Subscribe to:
POZ magazine
E-newsletters
Join POZ: Facebook MySpace Twitter Pinterest
Tumblr Google+ Flickr MySpace
POZ Personals
Sign In / Join
Username:
Password:

Back to home » Archives » POZ Magazine issues




Table of Contents

Detectable Rebels

Now See This

Editor's Letter-December 2004

Mailbox-December 2004

Down on the Pharma

Show and Tell

Pushing the Envelope

First, the Bad News

Milestones

Faster Forward

Prince Valiant

POS/NEG

Pregnant Pauses

Moonlighting Statins

They Soothe Tootsies, Don’t They?

Trouble in Mind

Pharm School

View from the Top



Most Popular Lessons

The HIV Life Cycle

Shingles

Herpes Simplex Virus

Syphilis & Neurosyphilis

Treatments for Opportunistic Infections (OIs)

What is AIDS & HIV?

Hepatitis & HIV


email print

December 2004

They Soothe Tootsies, Don’t They?

by Brett Moskowitz

Peripheral neuropathy (PN) numbs many an HIVer’s feet, hands or legs, making them tingle and swell, too. We’ve had painfully few PN therapies—and nukes like Zerit (d4T) or Videx (ddI) can worsen the condition. So here’s a sight for sore limbs: One month after getting the FDA OK for treating depression, Eli Lilly’s Cymbalta (duloxetine) was approved in September as the first pain reliever for diabetic PN. The drug regulates serotonin and norepinephrine, brain chemicals thought to rule both mood and pain sensation.

Cymbalta hasn’t been tested in HIVers, but similar meds have been shown to interact with protease inhibitors (PIs). However, David Simpson, MD, director of Mount Sinai’s Neuro-AIDS Program in Manhattan, calls the drug “worth pursuing in HIV PN.”

In two 12-week studies of more than 1,000 diabetics with PN, once-daily Cymbalta quickly reduced the amount of pain suffered over the course of a day. It also paid its snooze dues, helping trial subjects sleep without PN’s common night misery. Few stopped the med due to its minor side effects: nausea, constipation, dry mouth, diarrhea. Better a few runs than having feet that can’t.




[Go to top]

Join POZ Facebook Twitter Google+ MySpace YouTube Tumblr Flickr
Quick Links
Current Issue

HIV Testing
Safer Sex
Find a Date
Newly Diagnosed
HIV 101
Disclosing Your Status
Starting Treatment
Help Paying for Meds
Search for the Cure
POZ Stories
POZ Opinion
POZ Exclusives
Read the Blogs
Visit the Forums
Job Listings
Events Calendar


    dambitious
    Gone
    New York


    slimcuteguy
    Asheville
    North Carolina


    Heartland4now
    Tacoma
    Washington


    donnyp
    liberty
    Kentucky
Click here to join POZ Personals!
Ask POZ Pharmacist

Talk to Us
Poll
Survey
Pop Watch

more surveys
Contact Us
We welcome your comments!
[ about Smart + Strong | about POZ | POZ advisory board | partner links | advertising policy | advertise/contact us | site map]
© 2014 Smart + Strong. All Rights Reserved. Terms of use and Your privacy.
Smart + Strong® is a registered trademark of CDM Publishing, LLC.