November #96 : Warning Signs - by David Gelman, MD

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Table of Contents

Reversal of Fortune

Worlds Apart

There She Is...

Trial and Trial Again

Closing the Gap

African Bandstand

Pharma Adapts to ADAP

Stone Cold Killing

Hyper Activists

Who Gives a Fund?

Talkin' Turkey

Milestones

Can You Hear Me Now?

RETROPOZ: It Happened in November

Shout Out

Say What?

Paris is for HIVers

World on a (Shoe)string

Paris Scope: 6 Quick Picks from IAS

Bone UP

Bone Appétit

Guiding Light?

Quick Study: HPV and HAART

Heeling Power

Warning Signs

Drama Queen

Can Your Inner Ham

Burn, BABY, Burn

Mailbox

Sunshine State

Briefs



Most Popular Lessons

The HIV Life Cycle

Shingles

Herpes Simplex Virus

Syphilis & Neurosyphilis

Treatments for Opportunistic Infections (OIs)

What is AIDS & HIV?

Hepatitis & HIV


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November 2003

Warning Signs

by David Gelman, MD

Weak HAART: A combo of 3TC (Epivir) + abacavir (Ziagen) + tenofovir (Viread) seems too weak to fight HIV, warns Epivir and Ziagen-maker GlaxoSmithKline. Are you on this cocktail? Ask Doc about adding a fourth drug or switching your mix.

Inter act: Does your combo combine Viread with new one-a-day, lipid-friendly PI atazanavir (Reyataz) (see “New Meds on the Shelf,” POZ, October 2003)? Beware: Viread undercuts Reyataz’s ability to suppress HIV. Bristol-Myers Squibb, maker of Reyataz, says to add a 100-mg ritonavir (Norvir) booster. But will that bust the benefit of Reyataz by boosting lipids, too? Stay tuned.

Toxic TB tx: Lots of HIVers have latent TB infection (positive skin test but no illness)—and eradicating it reduces future risk of active TB. But the CDC now warns that one standard treatment, two months of pyrazinamide and rifampin, is too liver-toxic. So TB-positive HIVers are left with only one choice: nine months of slightly lighter-on-the-liver isoniazid (INH).




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