May #81 : Prime Time - by Mike Barr

POZ - Health, Life and HIV
Subscribe to:
POZ magazine
Join POZ: Facebook MySpace Twitter Pinterest
Tumblr Google+ Flickr MySpace
POZ Personals
Sign In / Join

Back to home » Archives » POZ Magazine issues

Table of Contents

Divinely Driven Dick

The Doctor Is Out

Say Aaaaah!



Loan Ranger

Raging Bull

Global Yodel

Bush 2, MaryJane 0


Afghan AIDS

Hemo Hero

Georgia on My Mind

I Want My HIV TV

Jock Sock


Spin Cycle

Seattle Rattle

Prime Time

Rhesus in Pieces

Fast Lane T Cells

Sustiva Diva

Coke Is It


Marathon Man

Love Handles

Publisher's Letter


Playing (for Keeps) in Poughkeepsie



Most Popular Lessons

The HIV Life Cycle


Herpes Simplex Virus

Syphilis & Neurosyphilis

Treatments for Opportunistic Infections (OIs)

What is AIDS & HIV?

Hepatitis & HIV

email print

May 2002

Prime Time

by Mike Barr

Merck & Co. had the Seattle confab buzzing by announcing a year-long safety test of its HIV vaccine in a small group of negative volunteers. In monkeys, the high-profile vax cut viral load sharply and slowed disease. If successful, the Merck vaccine not only would prove a boon for prevention but would also be fast-tracked for the treatment of HIVers.

The vaccine uses a "prime-boost" strategy -- two vax constructs are administered, one after the other. The primer takes advantage of "naked DNA" technology, as tiny fragments of HIV are injected directly into the muscle. The "boost" consists of an adenovirus "vector" -- a safe envelope into which HIV's gag protein is inserted.

The two-pronged strategy is designed to augment the killer-T cell ("CTL") attack against the virus. Response rates have been encouraging -- from 50 to 70 percent. Merck med head Emilio Emini says he plans to launch a study in some 600 HIVers in the near future.

[Go to top]

Facebook Twitter Google+ MySpace YouTube Tumblr Flickr Instagram
Quick Links
Current Issue

HIV Testing
Safer Sex
Find a Date
Newly Diagnosed
HIV 101
Disclosing Your Status
Starting Treatment
Help Paying for Meds
Search for the Cure
POZ Stories
POZ Opinion
POZ Exclusives
Read the Blogs
Visit the Forums
Job Listings
Events Calendar
POZ on Twitter

Ask POZ Pharmacist

Talk to Us
Did you participate in an event for National Black HIV/AIDS Awareness Day 2016?


more surveys
Contact Us
We welcome your comments!
[ about Smart + Strong | about POZ | POZ advisory board | partner links | advertising policy | advertise/contact us | site map]
© 2016 Smart + Strong. All Rights Reserved. Terms of use and Your privacy.
Smart + Strong® is a registered trademark of CDM Publishing, LLC.