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Table of Contents


Once Upon A Time...

Young At Heartland

The Lying Game

Life vs. Meth

This Is Only a Test

Mbeki's 180

Spin Doctors

Soda Wars

Iran Runs

New Friend

Sex Crimes

Got Milk? Get Meds

Got His Goat

Monkey C

Mind Trip

Beach Reads

Memory Lane

Face the Music

Failure Is Sweet

Who Done It

Defensive Tackle

Under the Sun

Cave Kava

Relayed Reaction

Habit Helpers

Ticked & Stoned

Rated X5

Vax Populi

TB or Not TB

IV Leader

Flower Children

Milestones

Drug Interactions

Dubya Trouble

Publisher's Letter

Mailbox

Reed Represents


Most Talked About

Does Undetectable Equal Uninfectious? (21)

Just Found Out? A POZ.com Guide for HIV Rookies (11)

The Blood of Christ (a powerful one-man AIDS protest) (Blog) (9)

The State of AIDS in Puerto Rico (9)

Rethinking Criminalization of HIV (8)

Life Expectancy With HIV Increases Dramatically (6)

Most Popular Lessons

The HIV Life Cycle

Herpes Simplex Virus

Human Papilloma Virus (HPV)

Shingles

Syphilis & Neurosyphilis

Treatments for Opportunistic Infections (OIs)



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July / August 2002


Monkey C

by Mike Barr

Study results from researchers at the National Cancer Institute (NCI) report an increased rate of DNA damage in the fetuses of monkeys treated with double-nucleoside analog therapy (AZT/3TC) compared to those of monkey moms who got AZT alone. How these findings apply to human fetuses exposed to AZT to prevent HIV transmission, however, is unclear. The fear is that nuke-induced mutations in the fetal DNA pose a risk for the development of certain cancers. A 1996 NCI study suggested a link between high-dose AZT and liver, lung and reproductive tumors in female mice, though a government review and a separate low-dose AZT study found no risk of tumors in humans. But the CDC says that it has not a single report of cancer in babies born to women taking AZT during pregnancy and that the immediate risk of HIV transmission is far greater than the theoretical risk of developing cancer in later life.

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