Kidney Health 1 : Mind Your Meds - by Tim Horn

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Mind Your Meds

by Tim Horn

Several medications, and some complementary therapies, can lead to kidney side effects. Discuss the following with your doc

Protease Inhibitors
Drug: Crixivan (indinavir)
Possible side effect: Formation of indinavir crystals, which are similar to painful kidney stones

Nucleotide Analogues
Drug: Tenofovir, the active ingredient in Viread and one of the drugs in Truvada and Atripla
Possible side effect: Accumulation in the kidney tubules, resulting in renal problems in a very small percentage of users

Nucleoside Analogues
Drugs: All, notably Zerit (stavudine) and Videx (didanosine)
Possible side effect: Rare acid buildup in the blood that can result in kidney failure

Complementary Therapies
Drugs: Chinese herbs containing sources of aristolochic acid, including Aristolochia, Bragantia and Osarum
Possible side effect: Chinese herbal nephropathy, leading to rapid kidney failure

Antibiotics
Drugs: Some meds that treat fungal infections, PCP and CMV
Possible side effect: A rapid shutdown of the kidneys

Nonsteroidal Anti-Inflammatory Drugs
Drugs: Advil (ibuprofen) and Aleve (naproxen)
Possible side effect: An allergic reaction known as interstitial nephritis, which can decrease blood flow inside the kidneys



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