June #60 : Mixed Messages - by Lark Lands

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Friend of Tinky

Brothers' Keeper

The New AIDS Look

Publisher's Letter


Death Of A Diva

Israel’s Madonna

Catching Up With...

Big Prison Break


The Maine Event

Say What?

Shout Out

Everybody’s Business

Bookmark This

Family Portrait, With Fidel

On Making A Hard Sell

The Riddle Of Limerick

Winter White

Stay On Course


Helping Hands

Smoke Alarm

Mixed Messages

PEP Rally

Herb Of The Month

Traveling The Light

Comfort Zone

E-Mail Bonding

What Big Enzymes You Have

Next Up…

Hot Off the Stress

6.30.89: Art Throb

Have HIV, Will Travel

Most Popular Lessons

The HIV Life Cycle


Herpes Simplex Virus

Syphilis & Neurosyphilis

Treatments for Opportunistic Infections (OIs)

What is AIDS & HIV?

Hepatitis & HIV

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June 2000

Mixed Messages

by Lark Lands

What’s In STORe for you if after starting HAART, your viral load goes down but your CD4 cells don’t rise, or your CD4s rise but your viral load doesn’t go down? New research suggests that when the two key measures of response to therapy are discordant, it’s the cells that may hold the crystal ball. In a Frankfurt study of 965 HIVers on HAART, one out of five had a good viral load response (a drop of greater than one log, or 90 percent) but no CD4 response (an increase of greater than 50 cells) after six months. During follow-up (23 months, on average), those who had a poor or no CD4 response—regardless of whether viral load significantly decreased—got sick or died faster than those whose CD4s improved along with their viral loads. In between were those whose CD4s went up but whose viral loads had a poor or no response. Bottom line: The CD4 count is what counts.

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