Treatment News : High-Dose Vitamins Don’t Fight HIV and Can Raise Liver Levels

POZ - Health, Life and HIV
Subscribe to:
POZ magazine
Newsletters
Join POZ: Facebook MySpace Twitter Pinterest
Tumblr Google+ Flickr MySpace
POZ Personals
Sign In / Join
Username:
Password:

Back to home » Treatment News » November 2012

Most Popular Links
Most Popular Lessons

The HIV Life Cycle

Shingles

Herpes Simplex Virus

Syphilis & Neurosyphilis

Treatments for Opportunistic Infections (OIs)

What is AIDS & HIV?

Hepatitis & HIV

15 Years Ago In POZ


More Treatment News

Click here for more news

Have news about HIV? Send press releases, news tips and other announcements to news@poz.com.


emailprint

November 28, 2012

High-Dose Vitamins Don’t Fight HIV and Can Raise Liver Levels

A large study has found that high doses of multivitamin supplements fail to combat HIV and may raise liver levels in those also taking antiretrovirals (ARVs), aidsmap reports.  Researchers from the Harvard School of Public Health published the results of their randomized, double-blind, controlled trial in The Journal of the American Medical Association.

The Harvard team recruited 3,418 HIV-positive people in seven clinics in Dar es Salaam, Tanzania, who were beginning ARV treatment between November 2006 and November 2008. Participants took daily oral supplements of either the recommended daily allowance of vitamin B complex, vitamin C and vitamin E, or between two and 21 times the dose of B vitamins, twice the dose of vitamin C and six times that of vitamin E.   

The study was halted early, in March 2009, because patients taking the high vitamin doses experienced elevated alanine transaminase (ALT) levels—which is an indication of liver damage. At that time, 3,418 people were still enrolled in the study for a median 15 months. High-dose vitamins had no effect on CD4 count, viral load, body mass index, mortality, or the risk of the blood disorders anemia and neutropenia.  However, 38 percent of participants in the high-dose arm experienced ALT levels that were elevated five times or greater than the upper limits of normal. Only 2 percent of those in the standard-dose arm experienced such elevations. 
The researchers noted that previous studies have shown that high doses of vitamins are safe for HIV-positive people, but because of “potential negative interactions among nutrients and antiretrovirals” the study authors advised those on ARVs to only take the standard dose of multivitamins.

To read the aidsmap report, click here.

To read the study abstract, click here.

Search: HIV, vitamins, high-dose, Harvard School of Public Health, antiretrovirals, Journal of the American Medical Association, Dar es Salaam, Tanzania, vitamin B complex, vitamin E, vitamin C, alanine transaminase, ALT, CD4 count, anemia, neutropenia, body mass index, viral load.


Scroll down to comment on this story.



Name:

(will display; 2-50 characters)

Email:

(will NOT display)

City:

(will display; optional)

Comment (500 characters left):

(Note: The POZ team reviews all comments before they are posted. Please do not include either ":" or "@" in your comment. The opinions expressed by people providing comments are theirs alone. They do not necessarily reflect the opinions of Smart + Strong, which is not responsible for the accuracy of any of the information supplied by people providing comments.)

Comments require captcha.
Please enter this number for verification:

| Posting Rules



Show comments (4 total)

 
[Go to top]


Facebook Twitter Google+ MySpace YouTube Tumblr Flickr Instagram
Quick Links
Current Issue

HIV Testing
Safer Sex
Find a Date
Newly Diagnosed
HIV 101
Disclosing Your Status
Starting Treatment
Help Paying for Meds
Search for the Cure
POZ Stories
POZ Opinion
POZ Exclusives
Read the Blogs
Visit the Forums
Job Listings
Events Calendar


    Hillcrester
    Ramona
    California


    Reginaldb06
    Dallas
    Texas


    max38man
    Chicago
    Illinois


    pozsmith1
    East Bay
    California
Click here to join POZ Personals!
Ask POZ Pharmacist

Talk to Us
Poll
Are you a regular coffee drinker?
Yes
No

Survey
Pop Watch

more surveys
Contact Us
We welcome your comments!
[ about Smart + Strong | about POZ | POZ advisory board | partner links | advertising policy | advertise/contact us | site map]
© 2014 Smart + Strong. All Rights Reserved. Terms of use and Your privacy.
Smart + Strong® is a registered trademark of CDM Publishing, LLC.