October/November #175 : Make Some Bones About It - by Laura Whitehorn

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From the Editor

Retiring the Ribbon


Letters- October/November 2011


High-Impact Prevention

What You Need to Know

Health Care Should Be a Human Right—for All

Too Few Pharma Companies in the Patent Pool

Legislation Proposed to End Criminal HIV Laws

AIDS Is Not an "Automatic Death Sentence"

Geckos Don’t Cure AIDS

We Hear You

The PrEP Debate

What Matters to You

Getting HIV Care Without Getting Deported

Treatment News

A Peek Into the Pipeline

Savvy Survival Strategy

Going Norvir-Free?

Cure Watch

Listen Up

Oh Baby!

Make Some Bones About It

Comfort Zone

Waiting to Inhale

POZ Heroes

Defying Gravity

Most Popular Lessons

The HIV Life Cycle


Herpes Simplex Virus

Syphilis & Neurosyphilis

Treatments for Opportunistic Infections (OIs)

What is AIDS & HIV?

Hepatitis & HIV

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October / November 2011

Make Some Bones About It

by Laura Whitehorn

A study by the Department of Veterans Affairs (VA) found that, while some HIV meds—in this trial, tenofovir (in Viread, Truvada and Atripla) and Kaletra (lopinavir/ritonavir)—can play a role in the disproportionately high incidence of bone fractures among people with HIV, the greater culprit is a mix of other risk factors including race, age, smoking, low weight, hepatitis C and diabetes. The study reviewed medical records of more than 56,000 positive people between 1988 and 2009.

But there’s still no need to panic, whichever meds you take: Fractures occur in fewer than two in 100 HIV-positive people.

In another study, Isentress (raltegravir) with Kaletra caused lower decline in bone mineral density (BMD) over 96 weeks. But don’t switch meds yet, says Roger Bedimo, MD, of the VA. Try calcium and vitamin D supplements while researchers “investigate whether discontinuing tenofovir will improve BMD and reduce fracture risk.”

Search: Department of Veterans Affairs, VA, tenofovir, Viread, Truvada, Atripla, Kaletra, race, age, smoking, hepatitis C diabetes, bone mineral density, BMD, fracture

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