October/November #175 : A Peek Into the Pipeline - by Laura Whitehorn

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Table of Contents
 

Features

R.I.P. HIV

From the Editor

Retiring the Ribbon

Feedback

Letters- October/November 2011

The POZ Q+A

High-Impact Prevention

What You Need to Know

Health Care Should Be a Human Right—for All

Too Few Pharma Companies in the Patent Pool

Legislation Proposed to End Criminal HIV Laws

AIDS Is Not an "Automatic Death Sentence"

Geckos Don’t Cure AIDS

We Hear You

The PrEP Debate

What Matters to You

Getting HIV Care Without Getting Deported

Treatment News

A Peek Into the Pipeline

Savvy Survival Strategy

Going Norvir-Free?

Cure Watch

Listen Up

Oh Baby!

Make Some Bones About It

Comfort Zone

Waiting to Inhale

POZ Heroes

Defying Gravity

   
Most Popular Lessons

The HIV Life Cycle

Shingles

Herpes Simplex Virus

Syphilis & Neurosyphilis

Treatments for Opportunistic Infections (OIs)

What is AIDS & HIV?

Hepatitis & HIV


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October / November 2011

A Peek Into the Pipeline

by Laura Whitehorn

A new entry inhibitor (EI) is in the works. Like the EIs already on the market, cenicriviroc (TBR-652) is designed to prevent HIV from invading immune cells to infect them.

And it might do more. The manufacturer, Tobira Therapeutics, says the drug may also calm the immune system and suppress inflammation. Here’s how: To keep HIV from entering cells, cenicriviroc blocks the CCR5 entry portal. But it also blocks CCR2, which is associated with increased inflammation. And inflammation is thought to cause many HIV-related health problems. Find more on cenicriviroc trials at clinicaltrials.gov.  

Search: entry inhibitor, EI, Tobira Therapeutics, cenicriviroc


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