May #144 : Protein Shakers

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Table of Contents
 

HIV: Behind the Music

Taking Care of Business




Not by Meds Alone

No Viral Load=No Transmission?

The Stand

Staphing Up

Mixology

Heads of the Class

Heartburn Hotel

Protein Shakers

Mercury Rising

Britain: Hep C Rings Twice

Pill-Taking Tip

Cardio Risk Raiser

Cholesterol Downer




What's a Girl to Do?

Runaway Hit

The Mother of All HIV Tests

Lights! Camera! Bareback Action!

Prom Night Prep

Apply as Directed

Strong-arming HIV

Healing Fields

Jargon: DWI

Keeping Up With the Joneses

Melrose Place 2.0

Silence=Meth

Rock Out

Ladies First




Editor's Letter-May 2008

Mailbox-May 2008



 
Most Popular Lessons

The HIV Life Cycle

Shingles

Herpes Simplex Virus

Syphilis & Neurosyphilis

Treatments for Opportunistic Infections (OIs)

What is AIDS & HIV?

Hepatitis & HIV


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May 2008


Protein Shakers

Proteins aren’t important just in your diet. More than 100,000 of them help your body’s cells do what they do—and some are providing the basis for future HIV meds.

Researchers recently identified 273 proteins that HIV uses as stepping-stones to infect and reproduce in the body. Once scientists ID them, they can study each
protein to see how it enables the virus. Meet three that have been getting attention—and learn how they can help you.

Name
Job
 Drug Contribution
CCR5
Acts as a lock on immune cells that HIV must pick before entering
Heped produce entry-inhibitor HIV meds, which block CCR5 so the virus can't get into a T cell 
APOBEC36
Can protect immune cells from infection--provided that an HIV protein ("vif") doesn't interfere
Understanding APOBEC3G's natural HIV-fighting ability--and its interaction with vif--may produce a slew of new drugs. 
P13K/Akt
Runs a pathway in cells that prevents infected ones from self-destructing (for your body to heal, this cellular suicide is neccesary)
 Has already helped produce a drug that allows parasite-infected cells to die off. That druge, miltefosine, is being studied to see if it will work against HIV, too.



 


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