July/August #173 : New and Improved Treatment for Hep C - by Laura Whitehorn

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Sisters Act

The Anal Dialogues

From the Editor



Letters- July/August 2011


Volunteer Mission

What You Need to Know

Kramer Makes Hearts Pound on Broadway

Nearly 7 Out of 10 Young People Are Having Sex

Film About Positive Kids Prevents HIV in Thailand

HIV Wasn’t a Motive for Triple Ax Murder

Angels Travel on Horseback in Southern Africa

Showcasing HIV Stigma in China

HIV Is (Officially) a Disability

96 Percent

We Hear You

Lips Unsealed

What Matters to You

How to Age With HIV—Gracefully

Treatment News

Help for Peripheral Neuropathy

HIV-Positive? Get Screened for Anal Cancer

Isolation Hurts Health

New and Improved Treatment for Hep C

MRSA Monster Tamed

Too Little Vitamin D Might Hurt Your Heart


Comfort Zone

Between the Covers

POZ Heroes

Each One, Reach One

Most Popular Lessons

The HIV Life Cycle


Herpes Simplex Virus

Syphilis & Neurosyphilis

Treatments for Opportunistic Infections (OIs)

What is AIDS & HIV?

Hepatitis & HIV

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July / August 2011

New and Improved Treatment for Hep C

by Laura Whitehorn

In the mid-1990s, protease inhibitors and combo therapy revolutionized HIV treatment, making it more effective and easier to take. Now hepatitis C’s moment is arriving, as new meds and strategies promise to improve therapy, even for people with hard-to-treat genotype 1.
  • New drugs: The FDA has approved two hep C protease inhibitors—Incivek (telaprevir) and Victrelis (boceprevir). Both promise to make standard treatment shorter for many and more effective for most. Alisporivir is the first in another new class, cyclophilin inhibitors, to get past the first clinical trials. All these must be taken with the standard interferon/ribavirin regimen.
  • Improved interferon: An experimental interferon—Peg-Interferon lambda (IFN λ)—appears to be more effective and cause fewer side effects than standard pegylated interferon alpha. (Both must be taken with ribavirin.)
  • Treatment without interferon: Several experimental drug combos look good in very early trials, attacking hep C without the standard pegylated interferon/ribavirin.
  • Statins: Combining a cholesterol-lowering drug (fluvastatin/Lescol did best) with standard hep C therapy improved people’s responses.
Get details and more at hepmag.com or search "Treatment Transformation" on poz.com  news.

Search: Hepatitis C, hep C, genotype 1, Incivek, telaprevir, Victrelis, boceprevir, Alisporivir, cyclophilin inhibitors, interferon, Peg Interferon lambda, ribavirin

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