September #174 : Test-Tube Babies - by Laura Whitehorn

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Table of Contents


All Grown Up With HIV

Facing the Future of HIV Care

From the Editor

The Facts of Life


Letters- September 2011


Going the Distance

What You Need to Know

The First Lady (Finally) Mentions HIV/AIDS

15M by 2015

Health Care for People With HIV in Grave Danger

Dame Elizabeth Taylor’s Jewels to Be Sold at Christie’s

Having Sex With Albino People Does Not Prevent or Cure AIDS

India-EU Trade Deal Could Put Millions With HIV at Risk

We Hear You

Judicial Prejudice and HIV

What Matters to You

Finding True Love With HIV

Treatment News

Test-Tube Babies

More Access to Medicaid for People With HIV

Help for Prisoners

FDA Approves a New HIV Drug

They’re Putting Viagra in Condoms???

By the Numbers

GMHC Treatment Issues September 2011

Comfort Zone

Life, in Harmony

POZ Heroes

Kid Wonder

Most Popular Lessons

The HIV Life Cycle


Herpes Simplex Virus

Syphilis & Neurosyphilis

Treatments for Opportunistic Infections (OIs)

What is AIDS & HIV?

Hepatitis & HIV

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September 2011

Test-Tube Babies

by Laura Whitehorn

Researchers have been experimenting with HIV drugs lately—not to lower viral loads (we already know how to do that), but for other health benefits. Here are some intriguing ways HIV meds might be used, all still in early experimental stages. Will these meds perform in your body as they do in the test tube? Stay tuned.
  • Fighting Cancer With Kaletra: The drug lopinavir (found in Kaletra) seems to kill cervical cells that have been infected with the human papillomavirus (HPV)—cells that can go on to become cancerous if left to their own devices. Lopinavir seems to target the precancerous cells without harming other cells in the cervix. The dose needed to shut down the cells is some 10 to 15 times higher than the lopinavir concentration in Kaletra, so researchers are developing and testing a high-potency topical version.
    • For women with HIV, who have much higher rates of HPV-related cancers than negative women, this could be a very useful development. And it seems likely that it would work on anal cells too, thus defending against HPV-related anal cancer.
  • Reducing Inflammation with Tenofovir or Selzentry: HIV not only kills off some immune cells, but also revs up the immune system, keeping cells active when they should be resting. Tenofovir (an HIV drug found in Viread, Truvada and Atripla) might suppress or reduce this chronic activity. This could, in turn, prevent some immune damage that takes place in people living with the virus—even when HIV meds are keeping their viral loads undetectable—and it may even help reduce the risk of conditions associated with inflammation.
And since 2009, Selzentry (maraviroc) has been known to suppress immune   inflammation. This entry inhibitor continues to be studied for that effect.

Search: cancer, Kaletra, lopinavir, human papillomavirus, HPV, tenofovir, selzentry, Viread, Truvada, Atripla, immune inflammation

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