Treatment News : Genital Warts Should Be Tested for Cancerous Cells

POZ - Health, Life and HIV
Subscribe to:
POZ magazine
E-newsletters
Join POZ: Facebook MySpace Twitter Pinterest
Tumblr Google+ Flickr MySpace
POZ Personals
Sign In / Join
Username:
Password:

Back to home » Treatment News » June 2010

Most Popular Links
Most Popular Lessons

The HIV Life Cycle

Shingles

Herpes Simplex Virus

Syphilis & Neurosyphilis

Treatments for Opportunistic Infections (OIs)

What is AIDS & HIV?

Hepatitis & HIV

15 Years Ago In POZ


More Treatment News

Click here for more news

Have news about HIV? Send press releases, news tips and other announcements to news@poz.com.


emailprint

June 9, 2010

Genital Warts Should Be Tested for Cancerous Cells

Anal warts in men who have sex with men (MSM) often contain cancerous and precancerous cells, an “unsettling” finding of a study reported in the July 1 issue of Clinical Infectious Diseases. The authors indicate that simply treating anal warts isn’t enough among MSM—they should be surgically removed and tested for high-grade cells that can potentially cause serious disease. 

Anal warts are typically caused by two non-cancerous strains of the same virus: human papillomavirus (HPV) types 6 and 11. Because of the perceived low risk of serious disease, many people with anal warts avoid treatment or opt for less invasive ablation procedures, such as cryotherapy (freezing the warts) or laser removal.  

The new findings, reported by Hans Schlecht, MD, of Drexel University College of Medicine in Philadelphia and his colleagues, suggest that surgical removal may be necessary in order to test for pre-cancerous and cancerous clusters within the warts. These high-grade patches of cells are often caused by two cancerous HPV strains, types 16 and 18. 

The study conducted by Schlecht’s group was designed to look for hidden, or “occult,” pre-cancerous or cancerous cells in anal warts surgically removed from 320 MSM. Fifty percent of the men enrolled in the study were living with HIV.
About 34 percent of the men had anal warts containing pre-cancerous cells. In fact, 3 percent of the men were found to have anal cancer. 

The high-grade cells were more likely to be documented in the warts taken from the HIV-positive men—47 percent compared with 26 percent of the HIV-negative men in the study. What’s more, seven of the eight men in the study diagnosed with anal cancer were coinfected with HIV. 

Unfortunately, neither a high CD4 cell count nor an undetectable viral load appeared protective against pre-cancerous and cancerous lesions among the HIV-positive men in the study. CD4 cell counts averaged 431, and about 50 percent of the men had viral loads below the level of detection at the time the high-grade lesions were detected. 

“The present study demonstrates that, in a large urban population of MSM, condylomata [anal warts] requiring surgical excision frequently harbored occult high-grade anal intraepithelial neoplasia or anal squamous cell cancer,” the authors concluded. “These data emphasize the importance of obtaining tissue for histopathological examination in MSM presenting for treatment of anogenital condylomata. Prevention of recurrences and careful clinical follow-up of anal condylomata harboring high-grade anal intraepithelial neoplasia may be a method of anal cancer prevention in MSM, particularly in those with HIV infection.”

Search: anal warts, condylomata, HPV, human papillomavirus, neoplasia, cancer, cancerous, pre-cancerous, surgery, ablation, cryotherapy


Scroll down to comment on this story.



Name:

(will display; 2-50 characters)

Email:

(will NOT display)

City:

(will display; optional)

Comment (500 characters left):

(Note: The POZ team reviews all comments before they are posted. Please do not include either ":" or "@" in your comment. The opinions expressed by people providing comments are theirs alone. They do not necessarily reflect the opinions of Smart + Strong, which is not responsible for the accuracy of any of the information supplied by people providing comments.)

Comments require captcha.
Please enter this number for verification:

| Posting Rules



Show comments (2 total)

 
[Go to top]


Join POZ Facebook Twitter Google+ MySpace YouTube Tumblr Flickr
Quick Links
Current Issue

HIV Testing
Safer Sex
Find a Date
Newly Diagnosed
HIV 101
Disclosing Your Status
Starting Treatment
Help Paying for Meds
Search for the Cure
POZ Stories
POZ Opinion
POZ Exclusives
Read the Blogs
Visit the Forums
Job Listings
Events Calendar


    Hillcrester
    Ramona
    California


    Sin_Grinder
    Reno
    Nevada


    Fred9774
    Brooklyn
    New York


    robert12
    Queens
    New York
Click here to join POZ Personals!
Ask POZ Pharmacist

Talk to Us
Poll
Have you ever been tested for hepatitis C?
Yes
No

Survey
Pop Watch

more surveys
Contact Us
We welcome your comments!
[ about Smart + Strong | about POZ | POZ advisory board | partner links | advertising policy | advertise/contact us | site map]
© 2014 Smart + Strong. All Rights Reserved. Terms of use and Your privacy.
Smart + Strong® is a registered trademark of CDM Publishing, LLC.