Treatment News : Heart Attack Risk Rises if CD4s Ever Dip Below 200

POZ - Health, Life and HIV
Subscribe to:
POZ magazine
Join POZ: Facebook MySpace Twitter Pinterest
Tumblr Google+ Flickr MySpace
POZ Personals
Sign In / Join

Back to home » Treatment News » November 2013

Most Popular Links
Most Popular Lessons

The HIV Life Cycle


Herpes Simplex Virus

Syphilis & Neurosyphilis

Treatments for Opportunistic Infections (OIs)

What is AIDS & HIV?

Hepatitis & HIV

20 Years Ago In POZ

More Treatment News

Click here for more news

Have news about HIV? Send press releases, news tips and other announcements to


November 11, 2013

Heart Attack Risk Rises if CD4s Ever Dip Below 200

The risk of heart attack among people with HIV is linked to a depleted immune system, specifically if CD4s dip below 200, aidsmap reports. Similarly, keeping CD4s at or above 500 means no greater risk for heart attack when compared with HIV-negative controls. Publishing their findings in the Journal of Acquired Immune Deficiency Syndromes, investigators conducted a case-controlled study of 22,081 people with HIV who were matched with 230,069 HIV-negative controls, all of whom received care through the Kaiser Permanente California health plan between 1996 and 2009.

With a mean 4.5 years of follow-up and 99,090 person years provided for analysis, the HIV-positive group experienced 283 heart attacks, for an incidence of 283 per 100,000 person–years. With a mean 5.4 years of follow-up and 1,253,550 person-years provided for analysis, the HIV-negative group experienced 2,064 heart attacks, for an incidence of 165 per 100,000 person-years.

After controlling for various factors, the researchers found that HIV on the whole was linked to a 44 percent increase in the likelihood of heart attack compared with HIV-negative controls. Those people with HIV who were taking antiretrovirals had a 50 percent increased risk of heart attack when compared with the controls.

Those HIV-positive people with either a current CD4 level below 200 or whose lowest-ever CD4 count dropped below this number had a respective 76 and 74 percent greater likelihood of heart attack when compared with the HIV-negative group. Those who never experienced a CD4 count at or below 500 had no greater risk of heart attack than the control group.

To read the study, click here.

To read the aidsmap story, click here.

Search: Heart attack, CD4s, aidsmap, 500, 200, Journal of Acquired Immune Deficiency Syndromes, Kaiser Permanente California.

Scroll down to comment on this story.


(will display; 2-50 characters)


(will NOT display)


(will display; optional)

Comment (500 characters left):

(Note: The POZ team reviews all comments before they are posted. Please do not include either ":" or "@" in your comment. The opinions expressed by people providing comments are theirs alone. They do not necessarily reflect the opinions of Smart + Strong, which is not responsible for the accuracy of any of the information supplied by people providing comments.)

Comments require captcha.
Please enter this number for verification:

| Posting Rules

Hide comments

Previous Comments:

  comments 1 - 1 (of 1 total)    

MarkNMelrose, Phoenix, 2013-11-13 11:15:58
My CD4 count has languished below 200 since 2005. I had open heart surgery to replace a mitral valve. I'm only 52 years old and my viral load is undetectable, yet this information leaves me feeling unsettled. You can bet I'll be discussing this with my healthcare team!

comments 1 - 1 (of 1 total)    

[Go to top]

Facebook Twitter Google+ MySpace YouTube Tumblr Flickr Instagram
Quick Links
Current Issue

HIV Testing
Safer Sex
Find a Date
Newly Diagnosed
HIV 101
Disclosing Your Status
Starting Treatment
Help Paying for Meds
Search for the Cure
POZ Stories
POZ Opinion
POZ Exclusives
Read the Blogs
Visit the Forums
Job Listings
Events Calendar
POZ on Twitter

Ask POZ Pharmacist

Talk to Us
Did you participate in an event for National Black HIV/AIDS Awareness Day 2016?


more surveys
Contact Us
We welcome your comments!
[ about Smart + Strong | about POZ | POZ advisory board | partner links | advertising policy | advertise/contact us | site map]
© 2016 Smart + Strong. All Rights Reserved. Terms of use and Your privacy.
Smart + Strong® is a registered trademark of CDM Publishing, LLC.