September #147 : Hep C Drug to the Rescue? - by Laura Whitehorn

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Table of Contents

The Castaways

Undress for Success

Stomaching Nausea

No Behind Left Behind

Hep C Drug to the Rescue?

Garlic Pill Warning

Mexicanos y HIV

Can Hypnosis Tame PN Pain?

Getting Out and Staying Healthy

Throwing the Book at Marijuana

Kidney News

Tribal Council

The Good Germs

Wedding Crashers

Running on Empty

The Freshman

Red-Carpet Ready


Please Do Stop His Music

The Incredible Bulk

M·A·C Attack

Birthday Girls

Editor's Letter-September 2008

Mailbox-September 2008


GMHC Treatment Issues-September 2008

Most Popular Lessons

The HIV Life Cycle


Herpes Simplex Virus

Syphilis & Neurosyphilis

Treatments for Opportunistic Infections (OIs)

What is AIDS & HIV?

Hepatitis & HIV

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September 2008

Hep C Drug to the Rescue?

by Laura Whitehorn

Hepatitis C (HCV), the liver-damaging virus that affects about 33 percent of HIV-positive people, is tough to treat. The standard therapy (Pegasys plus ribavirin) takes about a year, works in only about a third of those with HIV and often causes unpleasant side effects. So, for some time now, newer classes of hepatitis meds have been badly needed. Good news: A  front-runner in the development pipeline, telaprevir—a protease inhibitor for HCV—is steadily advancing.

In a recent Phase II trial, 65 percent of participants who added telaprevir to the standard hep C drugs for the first 12 weeks of treatment cleared HCV; only 45 percent of those taking just the standard drugs did. A bonus: In the telaprevir group, treatment time was cut from 12 months to six.

But there’s a catch. To date, telaprevir trials have excluded people with HIV. Theoretically, if approved,  “telaprevir should increase cure rates for coinfected people,” says Daniel Raymond of the Harm Reduction Coalition, “though I doubt it will shorten the duration of their treatment.”

Hey, why not include HIV positive people in trials and find out?

Search: HCV, hepatitis C

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