Newsfeed : Anti-HIV Molecule Might Block Transmission

POZ - Health, Life and HIV
Subscribe to:
POZ magazine
Join POZ: Facebook MySpace Twitter Pinterest
Tumblr Google+ Flickr MySpace
POZ Personals
Sign In / Join

Back to home » Newsfeed » January 2010

Most Popular Links
Most Popular Lessons

The HIV Life Cycle


Herpes Simplex Virus

Syphilis & Neurosyphilis

Treatments for Opportunistic Infections (OIs)

What is AIDS & HIV?

Hepatitis & HIV

20 Years Ago In POZ

More News

Click here for more news

Have news about HIV? Send press releases, news tips and other announcements to


January 5, 2010

Anti-HIV Molecule Might Block Transmission

U.S. investigators have found a molecule called surfen that can block HIV transmission, Voice of America News reports. The molecule, first described in 1939, is an anti-inflammatory and antibacterial agent that can bond to both HIV and white blood cells.

According to the article, HIV usually struggles to gain a foothold upon entering the body. However, a protein naturally produced in male seminal fluid, called SEVI, makes the virus 100,000 times more transferable than in its normal state. SEVI enhances HIV’s ability to cling to white blood cells and destroy the host immune system.

“What we have found is this small molecule by the name of surfen can block SEVI binding to HIV…and thus interrupt the infectious cycle or the transmission cycle,” said Warner Greene, MD, PhD, director of the Gladstone Institute of Virology and Immunology in San Francisco.

Despite failed attempts to use microbicide creams and gels with anti-HIV agents to prevent transmission, researchers believe surfen could impede infection by binding itself to HIV and the blood cells it targets.

“I think that the concept of using agents that target not only the virus but the host factor propelling the virus infection—I think that combination might produce a therapeutic synergy that could be quite effective,” Greene said.

Search: molecule, surfen, anti-inflammatory, antibacterial, SEVI, seminal fluid, Gladstone Institute of Virology and Immunology, microbicide

Scroll down to comment on this story.


(will display; 2-50 characters)


(will NOT display)


(will display; optional)

Comment (500 characters left):

(Note: The POZ team reviews all comments before they are posted. Please do not include either ":" or "@" in your comment. The opinions expressed by people providing comments are theirs alone. They do not necessarily reflect the opinions of Smart + Strong, which is not responsible for the accuracy of any of the information supplied by people providing comments.)

Comments require captcha.
Please enter this number for verification:

| Posting Rules

Show comments (0 total)

[Go to top]

Facebook Twitter Google+ MySpace YouTube Tumblr Flickr Instagram
Quick Links
Current Issue

HIV Testing
Safer Sex
Find a Date
Newly Diagnosed
HIV 101
Disclosing Your Status
Starting Treatment
Help Paying for Meds
Search for the Cure
POZ Stories
POZ Opinion
POZ Exclusives
Read the Blogs
Visit the Forums
Job Listings
Events Calendar
POZ on Twitter

Ask POZ Pharmacist

Talk to Us
Has a pet helped you deal with your HIV?


more surveys
Contact Us
We welcome your comments!
[ about Smart + Strong | about POZ | POZ advisory board | partner links | advertising policy | advertise/contact us | site map]
© 2016 Smart + Strong. All Rights Reserved. Terms of use and Your privacy.
Smart + Strong® is a registered trademark of CDM Publishing, LLC.