June #196 : Inflammatory Marker Linked to Raised Risk of Death - by Benjamin Ryan

POZ - Health, Life and HIV
Subscribe to:
POZ magazine
Join POZ: Facebook MySpace Twitter Pinterest
Tumblr Google+ Flickr MySpace
POZ Personals
Sign In / Join

Back to home » Archives » POZ Magazine issues

Table of Contents


POZ at 20

From the Editor

Alive and Kicking


Letters-June 2014


Survival by Design

POZ Planet

Meet the New AIDS Poster Child

POZ Stories: Byanca Parker

What’s the Diagnosis?

The State of Louisiana

I Have Something to Tell You

Say What? Egyptian Army Edition

Preppy Style

Law & Order

Positive Leadership


The New War

Care and Treatment

Seeing the Doctor Is Vital When CD4s Are Low

HIV Rates in Black MSM Linked to STIs and Economics

Inflammatory Marker Linked to Raised Risk of Death

Big Pharma Plotted to Prop Up South African Drug Patents

Half-baked Headlines Claim that Pot Stops HIV

Research Notes

Prevention: Genetically Tooled Antibodies Fight HIV

Treatment: Benefit of Counseling With Computers

Cure: Memory Stem Cells: Reservoir Backbone?

Concerns: Youths With HIV Enter Care Late

POZ Survey Says

Have You Been Tested?

POZ Heroes

Flesh and Blood

Most Popular Lessons

The HIV Life Cycle


Herpes Simplex Virus

Syphilis & Neurosyphilis

Treatments for Opportunistic Infections (OIs)

What is AIDS & HIV?

Hepatitis & HIV

email print

June 2014

Inflammatory Marker Linked to Raised Risk of Death

by Benjamin Ryan

Certain “markers” of inflammation in the body are linked to an earlier death among people with HIV, including those coinfected with hepatitis C. This possibly helps explain the reason why, even when treated for the virus, particular HIV-positive people die before others.

Researchers followed 400 HIV-positive alcohol abusers, half of whom also had hep C, for three to five years between 2001 and 2009. The participants were tested for seven pro-inflammatory cytokines, also known as markers, at the beginning of the study and then tracked to see if they died. (The study results are relevant to non-abusers as well.)

Cytokines are proteins that alert white blood cells to flock to a zone of inflammation. In the short term, this process is good for the body—it’s how fungal or bacterial infections are cleared, for example. But in the long-term it can be harmful.

The researchers found that higher indicators of inflammation were strongly linked to an increased risk of death, a connection that persisted regardless of whether or not an individual was taking ARVs. The inflammatory marker known as interleuken-6 (IL-6) had the most significant connection to mortality.

Study author Judith Tsui, MD, MPH, an assistant professor of medicine at Boston University School of Medicine, says, “I was actually surprised that IL-6 was so strongly associated with death, even 10 years later, after such a long follow-up period, which I think speaks to the fact that it is an important marker of inflammation.”

Search: inflammatory markers, hepatitis C, cytokines, interleuken-6, Judith Tsui, MD, MPH, Boston University School of Medicine

Scroll down to comment on this story.


(will display; 2-50 characters)


(will NOT display)


(will display; optional)

Comment (500 characters left):

(Note: The POZ team reviews all comments before they are posted. Please do not include either ":" or "@" in your comment. The opinions expressed by people providing comments are theirs alone. They do not necessarily reflect the opinions of Smart + Strong, which is not responsible for the accuracy of any of the information supplied by people providing comments.)

Comments require captcha.
Please enter this number for verification:

| Posting Rules

Show comments (0 total)

[Go to top]

Facebook Twitter Google+ MySpace YouTube Tumblr Flickr Instagram
Quick Links
Current Issue

HIV Testing
Safer Sex
Find a Date
Newly Diagnosed
HIV 101
Disclosing Your Status
Starting Treatment
Help Paying for Meds
Search for the Cure
POZ Stories
POZ Opinion
POZ Exclusives
Read the Blogs
Visit the Forums
Job Listings
Events Calendar
POZ on Twitter

Ask POZ Pharmacist

Talk to Us
Has a pet helped you deal with your HIV?


more surveys
Contact Us
We welcome your comments!
[ about Smart + Strong | about POZ | POZ advisory board | partner links | advertising policy | advertise/contact us | site map]
© 2016 Smart + Strong. All Rights Reserved. Terms of use and Your privacy.
Smart + Strong® is a registered trademark of CDM Publishing, LLC.