Treatment News : People With HIV Have High Risk of Invasive Pneumococcal Disease

POZ - Health, Life and HIV
Subscribe to:
POZ magazine
Join POZ: Facebook MySpace Twitter Pinterest
Tumblr Google+ Flickr MySpace
POZ Personals
Sign In / Join

Back to home » Treatment News » August 2014

Most Popular Lessons

The HIV Life Cycle


Herpes Simplex Virus

Syphilis & Neurosyphilis

Treatments for Opportunistic Infections (OIs)

What is AIDS & HIV?

Hepatitis & HIV

20 Years Ago In POZ

More Treatment News

Click here for more news

Have news about HIV? Send press releases, news tips and other announcements to


August 18, 2014

People With HIV Have High Risk of Invasive Pneumococcal Disease

Rates of invasive pneumococcal disease (IPD) are markedly higher among people living with HIV when compared with HIV-negative people, aidsmap reports. These diseases are infections caused by a bacterium; serious forms can include meningitis, pneumonia and sepsis (which affects the blood).

Publishing their findings in Clinical Infectious Diseases, researchers conducted a population-based cohort study of 5,362 HIV-positive Danes who received care at HIV treatment centers in Denmark between 1995 and 2012. These people were each matched with 19 HIV-negative controls, 101,869 people all told.

A total of 137 HIV-positive people and 136 of the controls were diagnosed with IPD during the years of the study, for respective incidences of 205 and 13 cases of IPD per 100,000 person-years of follow-up. Having HIV was associated with a 24-fold increased likelihood of developing IPD.

Among the people living with HIV, those who developed IPD were more likely to be female, to have a history of injection drug use, to have a lower current CD4 count and a lower CD4 count nadir, which is the lowest ever CD4 count.

As HIV treatments improved over time, the risk of developing IPD lowered among those living with HIV. However, during the modern era of combination antiretroviral treatment, the HIV-positive people still had a 19-fold increased likelihood of IPD when compared with the controls. For injection drug users (IDUs), there was no change in risk over time.

Among the HIV-positive people, smoking was associated with a 34 percent increased risk of IPD and injection drug use was linked to a 2.51-fold increased risk. Having a detectable viral load increased the risk by 88 percent. Having a lower CD4 count also increased the risk.

The only independent risk factor associated with death from IPD was age.

To read the aidsmap story, click here.

To read the study abstract, click here.

Search: Invasive pneumococcal disease, IPD, aidsmap, meningitis, pneumonia, sepsis, Clinical Infectious Disease, HIV.

Scroll down to comment on this story.


(will display; 2-50 characters)


(will NOT display)


(will display; optional)

Comment (500 characters left):

(Note: The POZ team reviews all comments before they are posted. Please do not include either ":" or "@" in your comment. The opinions expressed by people providing comments are theirs alone. They do not necessarily reflect the opinions of Smart + Strong, which is not responsible for the accuracy of any of the information supplied by people providing comments.)

Comments require captcha.
Please enter this number for verification:

| Posting Rules

Show comments (0 total)

[Go to top]

Facebook Twitter Google+ MySpace YouTube Tumblr Flickr Instagram
Quick Links
Current Issue

HIV Testing
Safer Sex
Find a Date
Newly Diagnosed
HIV 101
Disclosing Your Status
Starting Treatment
Help Paying for Meds
Search for the Cure
POZ Stories
POZ Opinion
POZ Exclusives
Read the Blogs
Visit the Forums
Job Listings
Events Calendar
POZ on Twitter

Ask POZ Pharmacist

Talk to Us
Did you participate in an event for National Black HIV/AIDS Awareness Day 2016?


more surveys
Contact Us
We welcome your comments!
[ about Smart + Strong | about POZ | POZ advisory board | partner links | advertising policy | advertise/contact us | site map]
© 2016 Smart + Strong. All Rights Reserved. Terms of use and Your privacy.
Smart + Strong® is a registered trademark of CDM Publishing, LLC.