October #158 : Word Up: HIV Sanctuary

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Table of Contents
 

Sex Crime

The Tales of Hofmann

Fighting for Our Freedom




Satisfy Yourself

Open Wide

Heart Beats

Go With the Flow

Change of Life Doesn’t Change Treatment

Word Up: HIV Sanctuary

Eye of the Storm

Berry Brouhaha




Condom Lockup

Greater Expectations

Recommended Reading

Radio Static

The Tamiflu Blues




Your Feedback-October 2009

Editor's Letter-October 2009

Making It Work



 
Most Popular Lessons

The HIV Life Cycle

Shingles

Herpes Simplex Virus

Syphilis & Neurosyphilis

Treatments for Opportunistic Infections (OIs)

What is AIDS & HIV?

Hepatitis & HIV


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October 2009


Word Up: HIV Sanctuary

Picture that wily little virus taking refuge from your meds, and you’ll grasp this term. HIV drugs attack only HIV-infected cells that are actively dividing—when responding to another infection, say. But meds can’t hit HIV in resting immune cells. So the meds can’t clear the virus from our bodies.

“HIV sanctuary” entered our vocabulary when researchers began trying to lure the lurking virus from its hideaways so the drugs could attack it. So far, that strategy hasn’t worked, because as drugs enticed hidden (latent) HIV to emerge, they also stimulated the immune system, creating more CD4 cells for the virus to infect.

Soon you’ll hear the term more frequently. In June, scientists showed just how these reservoirs keep HIV going, possibly laying the basis for a future strategy to coax HIV from its lairs without upping immune activity. Then, let’s hope, the hot term will be “HIV eradication.”

Search: HIV sanctuary, drugs, resting immune cells


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