Newsfeed : Mutation Destroys Gene for Type 2 Diabetes

POZ - Health, Life and HIV
Subscribe to:
POZ magazine
E-newsletters
Join POZ: Facebook MySpace Twitter Pinterest
Tumblr Google+ Flickr MySpace
POZ Personals
Sign In / Join
Username:
Password:

Back to home » Newsfeed » March 2014

Most Popular Links
Most Popular Lessons

The HIV Life Cycle

Shingles

Herpes Simplex Virus

Syphilis & Neurosyphilis

Treatments for Opportunistic Infections (OIs)

What is AIDS & HIV?

Hepatitis & HIV

15 Years Ago In POZ


More News

Click here for more news

Have news about HIV? Send press releases, news tips and other announcements to news@poz.com.


emailprint

March 5, 2014

Mutation Destroys Gene for Type 2 Diabetes

A new study based on the genetic information from 150,000 people has discovered a rare mutation that prevents even obese people from developing type 2 diabetes, The New York Times reports.

The Amgen data study, which was funded by Pfizer and published in the journal Nature Genetics, has revealed that the mutation reduces a person’s risk of developing the disease by nearly two-thirds.

The mutation works by destroying a gene in the pancreas called ZnT8. Without this genetic information, people seem to make slightly more insulin and have slightly lower blood glucose levels than normal throughout their lives. This protects them from ever developing diabetes, even when they have high risk factors for the disease, such as smoking, obesity or cardiovascular issues.

Researchers say the findings could lead to new drugs that may be able to mimic the gene’s effect. However, experts estimate development for these compounds would take at least 10 to 20 years to hit commercial markets.

This news also is of great relevance to people with HIV because they have elevated rates of diabetes.

To read the article, click here.

Search: Type 2, Diabetes, Amgen, Pfizer, Nature Genetics, gene mutation, ZnT8, prevention, HIV


Scroll down to comment on this story.



Name:

(will display; 2-50 characters)

Email:

(will NOT display)

City:

(will display; optional)

Comment (500 characters left):

(Note: The POZ team reviews all comments before they are posted. Please do not include either ":" or "@" in your comment. The opinions expressed by people providing comments are theirs alone. They do not necessarily reflect the opinions of Smart + Strong, which is not responsible for the accuracy of any of the information supplied by people providing comments.)

Comments require captcha.
Please enter this number for verification:

| Posting Rules



Show comments (0 total)

 
[Go to top]

Join POZ Facebook Twitter Google+ MySpace YouTube Tumblr Flickr
Quick Links
Current Issue

HIV Testing
Safer Sex
Find a Date
Newly Diagnosed
HIV 101
Disclosing Your Status
Starting Treatment
Help Paying for Meds
Search for the Cure
POZ Stories
POZ Opinion
POZ Exclusives
Read the Blogs
Visit the Forums
Job Listings
Events Calendar


    andais
    Red House
    West Virginia


    TanyaB
    Delray Beach
    Florida


    hollywoodvers1
    Los Angeles
    California


    blaze11212
    brooklyn
    New York
Click here to join POZ Personals!
Ask POZ Pharmacist

Talk to Us
Poll
Do you work with your doc to design your own treatment regimen?
Yes
No

Survey
PrEP Course

more surveys
Contact Us
We welcome your comments!
[ about Smart + Strong | about POZ | POZ advisory board | partner links | advertising policy | advertise/contact us | site map]
© 2014 Smart + Strong. All Rights Reserved. Terms of use and Your privacy.
Smart + Strong® is a registered trademark of CDM Publishing, LLC.