Treatment News : High CD4s Neutralize Raised Risk of Stroke in People With HIV

POZ - Health, Life and HIV
Subscribe to:
POZ magazine
Join POZ: Facebook MySpace Twitter Pinterest
Tumblr Google+ Flickr MySpace
POZ Personals
Sign In / Join

Back to home » Treatment News » June 2014

Most Popular Lessons

The HIV Life Cycle


Herpes Simplex Virus

Syphilis & Neurosyphilis

Treatments for Opportunistic Infections (OIs)

What is AIDS & HIV?

Hepatitis & HIV

20 Years Ago In POZ

More Treatment News

Click here for more news

Have news about HIV? Send press releases, news tips and other announcements to


June 25, 2014

High CD4s Neutralize Raised Risk of Stroke in People With HIV

People with HIV have a 40 percent greater chance of ischemic stroke than those without the virus; however, having high CD4 cells erases this increases risk. Publishing their findings in the journal AIDS, researchers conducted a cohort study of 24,768 HIV-positive people and 257,600 matched HIV-negative people who were members of Kaiser Permanente Northern and Southern California between 1996 and 2011.

There were 151 strokes among the HIV-positive participants, for a stroke rate of 125 per 100,000 person years, compared with 1,128 strokes among the HIV-negative participants, for a stroke rate of 74 per 100,000 person years. After adjusting for various factors, the researchers found that having HIV was linked to a 40 percent greater risk of stroke. However, when CD4 cells were higher than 500 among the HIV-positive participants, they had the same risk of stroke as the HIV-negative group.

“Recent CD4 cell count was the strongest HIV-specific risk factor, suggesting an effect of current immunodeficiency on ischemic stroke risk,” senior author Michael J. Silverberg, PhD, MPH, an investigator with the Kaiser Permanente Division of Research in Oakland, California, said in a release. “Notably, HIV-positive individuals with recent CD4 cell counts of 500 or more had no excess risk of ischemic stroke compared with HIV-negative individuals.”

“Given recent calls to reduce or abandon CD4 monitoring among HIV-positive individuals with viral suppression, our data suggest that the CD4 cell count may be useful beyond its role in HIV disease monitoring,” Julia L. Marcus, PhD, MPH, also with Kaiser’s Division of Research, said in the same release.

To read the press release, click here.

To read the journal abstract, click here.

Search: High CD4s, HIV, ischemic stroke, Kaiser Permanente, AIDS, Michael J. Silverberg, Julia L. Marcus.

Scroll down to comment on this story.


(will display; 2-50 characters)


(will NOT display)


(will display; optional)

Comment (500 characters left):

(Note: The POZ team reviews all comments before they are posted. Please do not include either ":" or "@" in your comment. The opinions expressed by people providing comments are theirs alone. They do not necessarily reflect the opinions of Smart + Strong, which is not responsible for the accuracy of any of the information supplied by people providing comments.)

Comments require captcha.
Please enter this number for verification:

| Posting Rules

Show comments (0 total)

[Go to top]

Facebook Twitter Google+ MySpace YouTube Tumblr Flickr Instagram
Quick Links
Current Issue

HIV Testing
Safer Sex
Find a Date
Newly Diagnosed
HIV 101
Disclosing Your Status
Starting Treatment
Help Paying for Meds
Search for the Cure
POZ Stories
POZ Opinion
POZ Exclusives
Read the Blogs
Visit the Forums
Job Listings
Events Calendar
POZ on Twitter

Ask POZ Pharmacist

Talk to Us
Did you participate in an event for National Black HIV/AIDS Awareness Day 2016?


more surveys
Contact Us
We welcome your comments!
[ about Smart + Strong | about POZ | POZ advisory board | partner links | advertising policy | advertise/contact us | site map]
© 2016 Smart + Strong. All Rights Reserved. Terms of use and Your privacy.
Smart + Strong® is a registered trademark of CDM Publishing, LLC.