Treatment News : Supplements That May Slow HIV Can Fuel Prostate Cancer

POZ - Health, Life and HIV
Subscribe to:
POZ magazine
Newsletters
Join POZ: Facebook MySpace Twitter Pinterest
Tumblr Google+ Flickr MySpace
POZ Personals
Sign In / Join
Username:
Password:

Back to home » Treatment News » February 2014

Most Popular Lessons

The HIV Life Cycle

Shingles

Herpes Simplex Virus

Syphilis & Neurosyphilis

Treatments for Opportunistic Infections (OIs)

What is AIDS & HIV?

Hepatitis & HIV

20 Years Ago In POZ


More Treatment News

Click here for more news

Have news about HIV? Send press releases, news tips and other announcements to news@poz.com.


emailprint

February 27, 2014

Supplements That May Slow HIV Can Fuel Prostate Cancer

High-dose supplementation with selenium and vitamin E can raise the risk of high-grade prostate cancer among certain men. This is of notable relevance to people living with HIV because of a recent study that found that supplementation with particular combination of multivitamins, including vitamin E, as well as with selenium, could slow HIV disease progression among those who are treatment naive and have a CD4 count above 350.

Publishing their findings in the Journal of the National Cancer Institute, researchers conducted a randomized, placebo-controlled trial involving 35,000 men who received high-dose vitamin E (400 IU per day), high-dose selenium (200 micrograms per day) or both. Designed to run for 12 years, the study started in 2001 but was halted early, in 2008, because it was apparent that selenium offered no protection against prostate cancer and it appeared that vitamin E might raise the risk. The men were then followed for an additional two years.

Among the men who started the study with a high level of selenium and who then took high-dose supplements of the element, the risk of prostate cancer increased by 91 percent. Their selenium levels became toxic.

The men who started with low selenium levels and who then took only high-dose vitamin E supplements raised their risk of prostate cancer by 63 percent and their risk of high-grade prostate cancer by 111 percent. Among the low-selenium participants, taking selenium in addition to vitamin E actually protected against vitamin E’s harmful effects.

“Many people think that dietary supplements are helpful or at the least innocuous. This is not true,” said corresponding and first author Alan Kristal, DrPH, a faculty member in the public health sciences division of Fred Hutchinson Cancer Research Center and the study’s lead author, said in a release. “We know from several other studies that some high-dose dietary supplements—that is, supplements that provide far more than the daily recommended intakes of micronutrients—increase cancer risk. We knew this based on randomized, controlled, double-blinded studies for folate and beta carotene, and now we know it for vitamin E and selenium.”

To read the press release, click here.

To read the study abstract, click here.

Search: HIV, supplements, vitamin E, selenium, prostate cancer, Journal of the National Cancer Institute, Alan Kristal, Fred Hutchinson Cancer Research Center.


Scroll down to comment on this story.



Name:

(will display; 2-50 characters)

Email:

(will NOT display)

City:

(will display; optional)

Comment (500 characters left):

(Note: The POZ team reviews all comments before they are posted. Please do not include either ":" or "@" in your comment. The opinions expressed by people providing comments are theirs alone. They do not necessarily reflect the opinions of Smart + Strong, which is not responsible for the accuracy of any of the information supplied by people providing comments.)

Comments require captcha.
Please enter this number for verification:

| Posting Rules



Hide comments

Previous Comments:


  comments 1 - 2 (of 2 total)    

Alabi JO M. Pharm, Warri-Nigeria, 2014-03-07 05:46:42
As part of Public Health Campaign, normal doses or daily recommendations of all micronutrients should be stressed. The implications of consummation of micronutrients from different sources of food and supplements should be emphasized. Our people should be encouraged to take intervention meals or supplements for a specified period when recommended. FDA should be involved.

SeaRickster, Seattle, 2014-03-05 13:40:13
Interesting research. I'm wondering if the conclusion (emphasis on 2nd to last paragraph, last sentence)is that it's okay to take low-dose selenium along with high-dose vitamin E. It's just that one should not take high-dose vitamin E (without selenium)and certainly not take high-dose selenium due to toxicity. Am I understanding this correctly... anyone?? Rick

comments 1 - 2 (of 2 total)    


[Go to top]


Facebook Twitter Google+ MySpace YouTube Tumblr Flickr Instagram
Quick Links
Current Issue

HIV Testing
Safer Sex
Find a Date
Newly Diagnosed
HIV 101
Disclosing Your Status
Starting Treatment
Help Paying for Meds
Search for the Cure
POZ Stories
POZ Opinion
POZ Exclusives
Read the Blogs
Visit the Forums
Job Listings
Events Calendar
POZ on Twitter

Ask POZ Pharmacist

Talk to Us
Poll
Are you buying holiday gifts that raise HIV/AIDS awareness?
Yes
No

Survey
Smoke Signals

more surveys
Contact Us
We welcome your comments!
[ about Smart + Strong | about POZ | POZ advisory board | partner links | advertising policy | advertise/contact us | site map]
© 2014 Smart + Strong. All Rights Reserved. Terms of use and Your privacy.
Smart + Strong® is a registered trademark of CDM Publishing, LLC.