After months of layoffs and service cuts, St. Vincent’s Hospital in New York City’s Greenwich Village officially closed April 30, The New York Times reports.

According to the article, the hospital’s last patients are 18 people in the Pax Christi Hospice, who have been allowed to remain. The hospital once accommodated more than 700 patients.

From the hospital’s founding in 1849, it provided medical care during many major events in New York City.

The hospital treated survivors from the Titanic and the September 11 terrorist attacks, as well as people with HIV/AIDS during the worst of the epidemic.