Two Duke research teams have received multiyear grants totaling $20 million for their work on HIV vaccines, according to Duke Medicine News and Communications. Both grants come from the National Institute of Allergy and Infectious Diseases (NIAID).

Mary Klotman, MD, of Duke University School of Medicine in North Carolina, and her team were awarded a $9 million five-year grant. They are researching an HIV vaccine based on a vector delivery strategy. Specifically, they’re work focuses on integrase defective lentiviral vectors, immunogen design and B cells.

In addition, an $11 million grant over five years goes to the collaborative efforts of Sallie Permar, MD, PhD, of the Department of Pediatrics at Duke, and researchers at the University of California, Davis, and the University of North Carolina. They are hoping to develop a maternal and infant vaccine to end pediatric HIV infections.