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I just came across this report, though I haven't seen very much published about its being widely adopted....I have been on Atripla for about 8 years, vl undetected / cd4 has been holding between 850-900. I get that the big pharma may not like this, but parts of this once a day drop off patent, and I think Atripla is no longer a go-to first line treatment, so could keep people on it and do less damage to their bodies (toxicity). I will see my ID doc in a few weeks and will discuss with him.
When I had begun to be treated, it was 9 years later with separate Efavirenz 600mg and combo Emtricitabin 200mg / Tenofovir 245mg once a day. Heavy effects of Efavirenz and high level of ratio in blood led to 400mg then 200mg with still good level of efficiency (undetectable). Just some strange dreams time to time but no more side effects now. Reducing Atripla dosed in 600mg of Efavirenz may induce curves of side effects so why don't reduce the ratio of Efavirenz in this combo for dayly use?
Oof I cannot imagine on medicine skipping doses..withdrawing every other day, that is not fun. Either every day or once a week maybe. Every other day? heck no.
Very important news for those patients struggling with costs or side effects such from daily Atripla. Now that there are newer combination once daily treatments available (e.g., Triumeq) has anyone looked to see if non-tenofovir regimens can also be taken on a less than daily schedule? What are the comparable half-lives of non-tenofovir combo drugs compared to Atripla?
This will make Big Pharma very angry. Lowering pills taken daily means lower profits for Big Pharma - and you and I know Big Pharma won't tolerate a cut in profit. They'll do everything to squash this.
no real news here . before changjng to genvoya, I was taking Atripla 5 days on 2 days off for five years . My vl was undetect and my cd4 was 1150 .
Great news and information on this drug treatment. This information can be discussed at clinics and community events to help those taking Atripla who leasing the cost and body usage of the drug.
StevenV1969
I just came across this article after a nurse told me I should not be taking my Atripla every other day. I started taking Atripla in 2007, I was switched from Sustiva/Truvada. I have been taking it every other day since I started. My Viral Load as ALWAYS been undetectable and my latest CD4 count was 535. It has NEVER gone below 500. After reading this article and a few others like it, there REALLY needs to be more testing done on the every other day / 3 times a week options.
June 15, 2018 • Santa Rosa, NM, USA