Generic Name: bictegravir + tenofovir alafenamide + emtricitabine
Abbreviation: BIC + TAF + FTC
Drug Class: Single-Tablet Regimens
Company: Gilead Sciences
Approval Status: Approved
Generic Version Available: No
Biktarvy has not yet been reviewed for inclusion in the DHHS list of recommended HIV treatments. Visit https://aidsinfo.nih.gov/guidelines/html/1/adult-and-adolescent-arv-guidelines/0 for the full DHHS guidelines.
Biktarvy is a single-tablet regimen for HIV. It contains an integrase inhibitor (bictegravir), a nucleotide reverse transcriptase inhibitor (tenofovir alafenamide), and a nucleoside reverse transcriptase inhibitor (emtricitabine). Biktarvy was approved by the U.S. Food and Drug Administration in February 2018.
Biktarvy should only be used by those with no history of HIV treatment failure and no known HIV mutations known to cause resistance to the individual components of the drug.
Bictegravir is not expected to be available as a standalone drug for use in combination with antiretrovirals other than tenofovir alafenamide (TAF) and emtricitabine (FTC).
Adult Dose: One tablet once a day. Each tablet contains 50 mg bictegravir, 25 mg tenofovir alafenamide, and 200 mg emtricitabine.
Pediatric Dose: N/A
Dosing Info: This is a complete one-pill, once-daily drug regimen. It can be taken with or without food.
The most common side effects were diarrhea, nausea and headache.
Similar to other integrase inhibitors, Biktarvy should not be taken at the same time as certain medications containing metal cations (such as calcium, magnesium, aluminum, and iron). Examples include certain antacids, laxatives, and mineral supplements. Generally speaking, these medications should be taken approximately two hours before or after Biktarvy.
Do not take Biktarvy with dofetilide or rifampin.
Before taking this medication, tell your doctor if you have kidney disease or liver disease (including hepatitis B). In addition, tell your doctor if you are pregnant or planning to become pregnant; if you are breast feeding, and all your medical conditions, including all prescription and over-the-counter medications and supplements you are taking.
Last Reviewed: February 7, 2018