#Genvoya

People who saw substantial CD4 T-cell gains during the first two years after diagnosis had better outcomes.

Many participants on two-drug regimens had more treatment under their belt and more chronic conditions.

However, all integrase inhibitors were associated with similar weight gain.

Switching to new tenofovir tied to improved bone health in older people with HIV

Advocates claim Gilead and others unfairly limited competition for HIV combination pills.

Researchers have called for revised treatment guidelines to address the higher risk of fracture in the HIV population.

Researchers at George Washington University take a look.

Participants entered the study taking tenofovir disoproxil fumarate, and some were switched to a regimen including tenofovir alafenamide.

Researchers at George Washington University take a look.

The newer tenofovir formulation can raise cholesterol and triglyceride levels, but these changes are reversible.

Swiss researchers analyzed shifts in kidney function among those switching from the old form of the HIV medication to the new one.

Currently, Gilead Sciences’ HIV regimen is not approved to treat drug-resistant virus.

That’s according to a study of 55 HIV-positive people with end-stage kidney failure.

Gilead has based its entire HIV drug portfolio on updating tenofovir, ostensibly to make it safer for bones and kidneys.