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The Mosaico study will enroll gay and bisexual men and transgender people at significant risk for the virus.
Given every four weeks, the combo injection of cabotegravir and Edurant (rilpivirine) will likely face an FDA decision by early 2020.
The trial will investigate whether injections of long-acting cabotegravir and rilpivirine yield a superior rate of viral suppression.
A machine learning algorithm designed small sets of proteins that boasted the greatest potential to elicit a broad-based immune response.
Pharma giants made agreements to keep prices high and block competition for generics, the civil lawsuit alleges.
Dosed every four weeks, the injection, which requires a clinic visit, includes long-acting rilpivirine and cabotegravir.
Researchers enrolled participants within 14 days of their HIV diagnosis.
Participants in a study were started on daily oral drugs and then half were switched over to long-acting meds.
Gilead has based its entire HIV drug portfolio on updating tenofovir, ostensibly to make it safer for bones and kidneys.
However, the regimen appears much less potent for those who aren’t virally suppressed.
Researchers call for closer cardiovascular monitoring for those switching from the TDF form of the drug to the TAF version.
Researchers have presented 96-week results from an advanced trial of Symtuza compared with Prezcobix plus Truvada.
Researchers compared switching to Symtuza with staying on an effective regimen of a boosted protease inhibitor plus Truvada.
The single-tablet antiretroviral regimen includes Janssen’s darunavir plus Gilead’s cobicistat, emtricitabine and tenofovir alafenamide.
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