March #186 : Pregnant Women Struggling With Adherence - by Benjamin Ryan

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Achieving the End

Falling Through the Cracks

From the Editor

Let's Stay Together


Letters-March 2013


Opening New Doors

POZ Planet

Turn Up the Music


Country Remedy

Promoting PrEP

Native Talents

Bare Facts

All Dolled Up

Tickled Pink


The 360 Approach

Care and Treatment

See You in Six Months?

Studying Risk Factors for Mental Decline

Implementing Health Care Reform

Pregnant Women Struggling With Adherence

GMHC Treatment Issues March 2013

HPV Vaccine May Benefit Women With HIV

Research Notes

Prevention: Latino Epidemic Varies by Region

Treatment: Atripla vs. Stribild and Complera

Cure: A Cat-and-Mouse Vaccine Game

Concerns: Ex-Inmates Aren’t Retained in Care

POZ Survey Says

Listen to Your Heart

POZ Heroes

Farewell, Friend

Most Popular Lessons

The HIV Life Cycle


Herpes Simplex Virus

Syphilis & Neurosyphilis

Treatments for Opportunistic Infections (OIs)

What is AIDS & HIV?

Hepatitis & HIV

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March 2013

Pregnant Women Struggling With Adherence

by Benjamin Ryan

Over a quarter of HIV-positive pregnant women and half of those during the postpartum period aren’t adhering to their antiretrovirals properly, putting them at risk of passing the virus along to their children, as well as experiencing treatment failure and developing drug resistance.

Publishing their findings in the journal AIDS, researchers from Johns Hopkins University Bloomberg School of Public Health conducted a review of 51 studies of over 20,000 HIV-positive pregnant women in the United States, Kenya, South Africa and Zambia. Only 73.5 percent of the pregnant women and 53 percent of those during postpartum were greater than 80 percent adherent to their meds.

“That really was for us quite a shock,” said lead researcher Jean Nachega, MD, PhD, an infectious disease internist and an associate professor at Johns Hopkins. “That’s the population that should have optimum adherence, but the reality is just the opposite. Our paper was a wake-up call.”

Multiple factors influenced these troubling statistics: poverty, pill burden, drug and alcohol use, as well as mental health factors, most notably post-partum depression. On the other hand, women who disclosed their HIV status and who had a strong social support system had higher levels of adherence. Nachega said further research is urgently needed to design successful interventions for this population.

Search: HIV, HIV positive pregnant women, antiretrovirals, women, health

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