Under a new label change, anyone taking Reyataz (atazanavir) and Videx EC (ddI) in the same combo is urged to dose separately: Reyataz should be taken with food two hours before or one hour after Videx EC. Also, heartburn sufferers can be on Reyataz while taking an H2 antagonist—but only if you take the Reyataz (with food) either two hours before or ten hours after. Proton-pump inhibitors are still a no-no.