In this special World AIDS Day episode of HIV unmuted, the IAS podcast, we share the human endeavours behind the journey to a cure.

The Esperanza Patient has no evidence of intact HIV blueprints that can produce more virus.

HIV cure studies have led to many disappointments, but researchers continue to explore ways to achieve sustained viral remission.

One new approach protects CD4 cells against HIV entry, while another snips out viral genes in infected cells.

Different mechanisms suppressed the virus in each person.

Timothy Ray Brown, the first person cured of HIV, died last year. An engraved boulder in the National AIDS Memorial Grove honors him.

NIH-funded study finds reduced levels of HIV in bone marrow, spleen and brain after nanoparticle therapy.

Scientists are getting a better sense of the risks and benefits of treatment interruptions in cure research.

The National Institutes of Health awarded grants for HIV cure research to these 10 organizations. One focuses on pediatric populations.