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#Cure

Experimental Agent Shrinks HIV Reservoir, but Fails to Delay Viral Rebound
#Prevention
#PrEP

All the AIDS Conference News That’s Fit to Print

A speedy overview of the major scientific findings presented at the International AIDS Conference in Amsterdam (AIDS 2018)

First Attempt at Randomized HIV Cure Trial Yields Disappointment

The “kick-and-kill” strategy—waking up latently infected immune cells so as to kill them—did not reduce participants’ viral DNA.

HIV Cure Treatment Is Promising in Monkeys, Fails in Humans

This disappointment highlights the challenge of translating animal research into human trials.

New Gene-Editing Method Could Revolutionize HIV Cure Efforts

Scientists have discovered a swifter and more precise way to edit the genome of immune cells, opening doors for cancer and HIV therapies.
The first vaccination of HVTN 702 at the Versulam clinic in Durban South Africa

Viral Basics

Understanding the importance of basic HIV research and clinical trials—and the benefits of being undetectable

Cure: Research Ethics

Findings provide reassurance on ethics of cure studies.

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#Long-Term Survivors
#Life Expectancy
#Newly Diagnosed

“Super Receptor” on Immune Cells May Hold Key to HIV Cure Research

Scientists found this receptor on the CD4 cells of so-called elite controllers of the virus.

Your Opinion Matters!

Take a survey on HIV cure research.
David Wohl, MD, of University of North Carolina School of Medicine

This New Podcast Explores Living a Long Life With HIV

It’s just one episode of “HIV Matters,” a (free!) podcast series from the University of North Carolina’s Department of Medicine.

“Shock and Kill” HIV Cure Method May Be Too Anemic to Work

A recent study found that agents used to wake up resting HIV-infected cells probably work only on 5 percent of such cells.

Cure: Delaying Rebound

Scientists tested the effects of the broadly neutralizing antibody PGT121 and the immune-stimulating agent GS-9620 in monkeys.

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HIV: The Basics
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Crystal Meth May Lead Even Well-Treated HIV to Further Harm the Body

According to a pair of recent studies, meth was associated with certain HIV-related genetic and immune changes.

Gene-Editing Study in Monkeys Sets Stage for Further HIV Cure Research

Scientists succeeded in editing the animals’ stem cells to resist an HIV-like virus and ultimately shrink their viral reservoir.
A CD4 cell

Molecule Thought to Indicate HIV Reservoir Actually Does Not

Researchers say CD32 is not a biomarker for immune cells latently infected with HIV but one for actively infected cells.

The Role of Vaccines and Cures in HIV Elimination

An update from the director of the Basic Science, Vaccines and Cure Project at Treatment Action Group (TAG).

Is Curing Patients Good for Business? Asks Goldman Sachs Biotech Report

For example: Hep C cures have meant fewer people to treat and fewer transmissions to potential patients.
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