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Credit to these guys for think about this. Enough minds together will overcome!
Just to follow up, the paper (which is open access) does explicitly discuss the possibility of an impact on T cell function, the authors feel the change in viral load should have been faster if it was caused by T cell responses. There's also some info suggesting mutations in the virus due to an anti-HIV effect of the antibodies.
The finding may not actually be related to antibodies, which are rarely able to mediate significant anti-HIV activity. B cells also have a role in generating and sustaining T cell responses, so depleting B cells may impact viral load control by impairing HIV-specific CD4 T cell and CD8 T cells.
tagbasicscienceproject.typepad.com/tags_basic_science_vaccin/2009/02/a-role-for-b-cells-in-the-development-of-cd4-t-cell-memory.html
mike
can some one please tell me is there a better meds than atripla which is one a day, today in the market? thank you
October 27, 2010