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Path to a Cure? The Risk and Promise of Gene Therapy

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11 Comments

John

Some believes that it is still possible that hiv could binding the CXCR4 receptor even in the german patient that has been treated, and cured, by a bone marrow transplant. How is possible for hiv (if there is still hiv in the latent reservoirs that can not be detected by any HIV DNA PCR ) to evolve if there is no active replication ?

December 9, 2008

D. Louis

I recently losted a love one to this devastating disease, I don't want to die of complications to AIDS, how can I become a volunteer participant in stem cell research?

December 8, 2008 Dallas, Texas

kris

please find the cure

December 7, 2008

polonio210

Very clear and updated article. It's time to send HIV/AIDS stories to the past. Thanks

December 5, 2008

celestialdrmz_4u

As a Hodgkin's survivor & 25 year poz female, this option is not a new idea. I actually thought something such as this treatment originally used for just lymphomas may well work for HIV too. However, as my remission from lymphoma was/is considered nothing short of miraculous (that I survived chemo & radiation while CD4 below 200)-it certainly isn't a treatment option, that should it become available, would be for everyone. Do some homework in cancer therapies people. It may be our only hope!

December 5, 2008 East Bay

Kirk

I am encouraged because of the options and thoughtful considerations. If this is proven to be correct, that this man is cured of HIV, it will be replicated again and again. Even if the cost is prohibitive, human-kind will find ways to produce it for many others as well. I like the article because it shows that there is so much to learn and so much opportunity for our world (not fatalism). I think the cure for HIV is probably related, greatly, to gene therapy!

December 4, 2008 Dallas/Fort Worth

Jonathan

they say $250,000.00 is allot? thats like 2.5 years worth of my medication. wouldnt it be worth it to pay 1/4 milion to stop paying over $100,000 a year in jkust my meds (not to mention blood tests, doctors, ect)

December 4, 2008 Apache Junction

Jay

Here's something really cool. In the above article (thanks, David!), Dr. Scadden refers to "a paper [on research that found] in a mouse you could use an antibody" to clear out existing stem cells without using chemotherapy or radiation. Well, here's the synopsis of the paper. Published in November 2007 by a group at Stanford Medical School www.ncbi.nlm.nih.gov/pubmed/18033883 This approach coupled with transplantation of modified stem cells lacking a CCR5 receptor just might...?

December 4, 2008 NC

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