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I am suffering fom abnormal kidney funtion and osteoporosis, this condition only began after I started HIV meds. The people at the clinic I attend do not seem to really concern themselves with my overall health, they are only cocerned with lowering my viral load. I find this kind of treatment offensive, they have no compassion. The drug companies do not seek to cure but only make money, chemo therepy is no cure for cancer or AIDS, yet makes the Pharmaceutical Corporations and Government rich.
Dr. Fitzgibbons - Please know that the authors of this study did not specify type(s) of tubular damage in the patients and widely used terms like "dysfunction" and "impairment" without further clarification. This catch-all term applied to anyone with at least two altered serum or urine parameters, with at least one of them being nondiabetic glucosuria, reduced tubular resorption of phosphorous or pathologic aminoaciduria.
I am deeply concerned that Tenofovir continues to be prescribed and used as broadly as all appearances indicate. It was a critical factor in sending me into renal failure and the ICU two years ago, and I count myself fortunate (a.) to have survived at all and (b.) to have avoided dialysis -- the latter to the great surprise of my medical providers. This has been an unpleasant ride, and I would fear for anyone who had less access to extensive care than I.
I could not figure out from your story whether you meant renal tubular acidosis, acute tubular necrosis (which may require dialysis) or just some relatively minor leak in the filtering system. "Tubular dysfunction" is so vague as to be meaningless, and a doctor who is asked about it will think they got it from some unreliable source and disregard it. Please use the technical term and explain what it means and how to test for it.
Paul C
I am 60 and on tenofovir (in Truvada) and have sudden onset hypertension (160/110)after being on Truvada for 6 years. My MD has chosen to treat me for pulmonary hypertension, but I suspect this could also be related to hypokalemia (low potassium) from kidney effects of tenofovir. My MD did not even raise this issue. Just prescribed an anti-hypertensive which not showing very immediate relief. I think it would make sense to drop Truvada in older, longterm HAART takers.
July 12, 2009 • Boston