Write a Comment
8 Comments
So what are the implications for "clearing the resevoirs"?
Jeton, How did you get your doc to prescribe you minocycline off label for such a long time?
well, to protect my brain better since 2005 i've been on minocycline twice daily, as well as haart meds that penetrate CNS. i won't be stopping without better proof than this. beware tho, minocycline n reyataz do not mix.
Great! I've seen (as have many others) what one looks like as they die from brain inflammation and loss of general facilities as their brial was taken over from AIDS. Guess (thanks to the Reagan Administration) most of us will have something to keep looking forward to. Hmm, they still shoot horses don't they when nothing more can be done? I lost my short term memory among other things before diagnoses (1995). Wonder what else we have to look forward to.
It´s a very interesting and important study indeed. Congratulations! We all hope that it could help acelerate other studies toward better treatment regimenes and, who knows, toward a cure.
Hi J - No, Sustiva wasn't used in this study. While Sustiva is known for its CNS side effects -- like vivid dreams and muddled thinking -- it actually doesn't penetrate the CNS as well as some other HIV drugs.
There's no mention of Sustiva in this article and I have always been under the impression that the primary benefit of Sustiva was that it crosses the blood brain barrier and entered the CNS. Is this not true, or was Sustiva not a part of this study?
Jeton Ademaj
David, the initial John Hopkins pilot study of minocycline in SIV-infected chimps became public access in Oct. 05, at the same time as a flurry of news articles indicating that HIV replicates in the brain despite ARV. i simply presented ALL of this to my doc, along with an extensive argument about the particulars of my own health history. i fought hard, n my doc was open-minded to begin with. since then, minocycline has gained more HIV-kudos...check wikipedia.
December 14, 2010 • Harlem, NYC