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#Africa

Very Low CD4 Count Linked to Highest Death Risk After Starting HIV Treatment

A recent study in Africa parsed the factors that predicted death after people with a CD4 count below 100 started antiretrovirals.

Isentress Doesn’t Raise Risk of “IRIS” in Those With Very Advanced HIV Disease

Immune reconstitution inflammatory syndrome (IRIS) can occur when individuals with low CD4 counts begin HIV treatment.
Robert R. Redfield, MD

Amid Criticism, HIV Researcher Robert Redfield Is Named Director of CDC

In the past, he was accused of misusing data, showing religious bias and discriminating against gay men and people with HIV.

Vaginal Inflammation Lowers Effectiveness of HIV-Preventing Gel

An analysis of a previous study of a tenofovir-based vaginal gel found that women with vaginal inflammation were less protected.
The opening session of CROI 2018 in Boston.

The Best of CROI 2018

Highlights from HIV and hepatitis C research presented at the 2018 Conference on Retroviruses and Opportunistic Infections (CROI) in Boston

A Uganda District’s HIV Rate Halved as Treatment and Circumcision Rises

An analysis of a fishing community yields some of the first evidence of the overall efficacy of a combination approach to prevention.

Hard-Hit Lesotho Makes Progress in HIV Testing and Treatment

A nationwide household survey indicated that 61 percent of the nation’s HIV population had a fully suppressed viral load.

Vaginal Ring Appears to Cut Women’s HIV Rate in Half in New Study

The open-label follow-up to a previous placebo-controlled study of an HIV-preventing ring is seeing high use among women.

Women’s HIV Risk Rises in Late Pregnancy and Postpartum Period

According to recent studies, this shift in risk is likely driven by biological, and not just behavioral, factors.

An Exciting Act II for the Study That Proved Treating HIV Early Is Best

With a grant to follow their large study population through 2021, researchers hope to gain vital new insights about HIV infection.

Starting HIV Meds Before Conception Raises Risk of Underweight Newborns

Nevertheless, the benefits of HIV treatment for both the mother and unborn child far outweigh any such risk.
A CD4 cell

Levels of CD4 Cells With Gut-Homing Protein Are Linked to HIV Risk

Researchers discovered that higher levels of such cells were tied not only to infection risk but also HIV disease progression.

Rate of Detectable Virus in HIV Population May Be Poor Sign of Transmission Risk

Looking to the proportion of people with HIV with an undetectable viral load does not account for changes in the overall prevalence of HIV.

18 Months of HIV Prophylaxis Is Safe and Effective for Breast-Feeding Mothers

This is according to extended follow-up of a trial that gave HIV-positive breast-feeding mothers treatment or prophylaxis for their infant.

HIV Drug Resistance Is Increasing in Africa and Latin America

The high proportion of individuals starting treatment with drug resistance already warrants changing the recommended first-line therapy.

Do HIV-Preventing Microbicides Have a Future in the Age of PrEP?

Courting controversy, the NIH considers a shift away from the development of new vaginal or rectal-based HIV prevention products.
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