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On-demand, or 2-1-1, PrEP requires taking only four doses of Truvada during the days surrounding sex.
A mathematical modeling study projected the effect of routine STI screening among a population of gay and bi men on PrEP.
Among nearly 10,000 gay and bisexual men followed for a cumulative 18,000 years, there have been only 16 new cases of the virus.
The Mosaico study will enroll gay and bisexual men and transgender people at significant risk for the virus.
Electronic prompts for clinicians to recommend Truvada to people at risk for HIV could help increase PrEP’s impact.
On-demand PrEP is taken only during the days surrounding sex.
In the past 18 months, 42 people who use drugs tested HIV positive in Multnomah County, which includes Portland.
Previously, tests were approved only for use with genital or urine samples.
Untreated sexually transmitted infections can lead to pelvic inflammatory disease, which can complicate women’s ability to get pregnant.
Douching before receptive anal sex may damage the delicate lining of the rectum and flush out protective bacteria.
A quarter of study participants accounted for three-quarters of newly diagnosed cases of chlamydia, gonorrhea and syphilis.
Researchers suggest that using antiseptic mouthwash may mitigate this risk.
New HIV cases in the city remain higher than those in Los Angeles County and the state.
However, because this combo is not as effective as the current standard treatment, the search for new options continues.
“Humberto truly understood the plight of people on the margins of society, of people who have the least access to health care.”
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