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Researchers hope to combine gene editing with a less toxic stem cell transplant. Findings may apply to cancer and other illnesses.
Researchers studied 16 people with HIV who had received a stem cell transplant for blood cancer.
“I want to be an ambassador of hope,” Adam Castillejo, 40, who grew up in Venezuela, tells The New York Times.
Trying to mimic the “Berlin Patient” cure, researchers edited the CCR5 gene in the immune stem cells of a man with leukemia and HIV.
The increasing mastery over the virus is one of humanity’s crowning achievements.
A second man’s virus went into remission following an HIV-resistant stem cell transplant to treat his cancer.
The Conference on Retroviruses and Opportunistic Infections in Seattle saw many important studies that are advancing the fight against HIV.
“The Düsseldorf Patient” has been off HIV meds only since November 2018, so it is much too early to determine whether he has been cured.
Perhaps amfAR sums it up best: “We’re certainly hopeful.”
Today, with better understanding of the complex task at hand, cure researchers are investigating multiple avenues and taking the long view.
Ten HIV-positive cancer patients to receive donated cord blood with rare resistance gene.
A new study analyzes nuances in a cohort of six people who also received stem cell transplants for blood cancers.
Scientists succeeded in editing the animals’ stem cells to resist an HIV-like virus and ultimately shrink their viral reservoir.
The drug is approved to cut the risk of CMV reactivation following a stem cell transplant.
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