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The newer tenofovir formulation can raise cholesterol and triglyceride levels, but these changes are reversible.
This will provide free PrEP to as many as 200,000 uninsured Americans until 2030.
Only one company will sell a version of the HIV prevention pill Truvada. When others go to market, prices will likely drop further.
Two men claim they developed bone and kidney problems after taking TDF. A related class action lawsuit has also been filed.
An analysis of a previous study of a tenofovir-based vaginal gel found that women with vaginal inflammation were less protected.
Largest-ever analysis of bone loss in the HIV population found that treating hep C, taking vitamin D and exercising might be preventive.
New trial compares Descovy to Truvada.
The AIDS Healthcare Foundation alleges Gilead could have developed the safer version of tenofovir earlier.
Increases may be designed to push patients to the company’s newer regimens.
The FDA has approved the single-tablet antiretroviral regimen Odefsey, which includes a new, safer version of tenofovir.
The FDA has approved Gilead Science’s Genvoya, which is the first HIV treatment to include an updated version of tenofovir.
Among people who fail HIV treatment, resistance to tenofovir is common, and the incidence of such acquired resistance is likely increasing.
Lawsuit: Gilead has manipulated the patent system to extend its control (and profit) of tenofovir, found in many HIV regimens.
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