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#tenofovir disoproxil fumarate

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FDA Approves Three New, Cheaper Combination ARV Tablets
Tenofovir Disoproxil Fumarate 101
Chart of Approved and Experimental HIV Medications

Do Integrase Inhibitors Raise the Risk of Cardiovascular Disease?

Certain drugs in this class may increase the likelihood of diabetes and hypertension, but cardiovascular risk factors can be managed.

Tenofovir and COVID: The Jury Is Still Out

Research on the links between tenofovir and other antiretrovirals, SARS-CoV-2 infection and COVID severity has produced mixed results.

A Peek at Big Pharma’s Playbook That Leaves Many Americans Unable to Afford Their Drugs

In the 1980s, AZT was labeled the most expensive drug in history at $8,000 annually. Now, scores of drugs cost more than $50,000 a year.

PrEP Exposure Before Birth Doesn’t Harm Children’s Bones

At three years, median height and bone mineral density were similar for children with and without tenofovir exposure in the womb.
Descovy and Truvada

HIV Drugmaker Gilead Delayed Newer Version of Tenofovir to Extend Profits

Internal documents show Gilead held off on developing new therapies, such as Descovy, a potentially less toxic version of Truvada.

Daily Oral PrEP Is Effective for Women

TDF/FTC is effective for cisgender women who take at least four pills per week, but many struggle to reach this level of adherence.

More Studies Explore Weight Gain Linked to HIV Treatment

Disruption of fat metabolism and altered gut microbiome may help explain weight changes associated with antiretroviral therapy.

Much Remains to Be Learned About Long COVID

Several mechanisms may play a role, including persistent virus and ongoing immune dysregulation.

Kidney Problems Are Uncommon Among People Taking PrEP Pills

Changes in kidney function were small for those using TDF/FTC either daily or on-demand for HIV prevention.

Switching From New to Old Tenofovir May Reverse Weight Gain

Switching from TAF to TDF may help people lose weight, but this must be balanced against the risk of kidney problems and bone loss.

IAS-USA Releases New HIV Treatment and PrEP Guidelines

The updated guidance says antiretroviral therapy should be started as soon as possible after diagnosis and outlines the latest options.

Most Women Know About PrEP, but Few Are Using It

Although 71% of survey respondents were aware of PrEP, just 19% had ever used HIV prevention pills.

New Study Sheds More Light on Tenofovir and COVID-19

Research on links between tenofovir, SARS-CoV-2 infection and COVID severity have yielded mixed results, but new study suggests it helps.

Does Prenatal PrEP Exposure Affect Outcomes in Children?

Children born to mothers on PrEP appeared to have normal growth and cognitive development.

A Decade After Approval, PrEP Hasn’t Reached its Full Potential

The prevention pills—and newer methods—have averted countless HIV cases, but they still aren’t reaching everyone who could benefit.

On-Demand PrEP Works as Well as Daily Pills

The PrEP 2-1-1 regimen offers an option to take HIV prevention pills before and after sex instead of every day.
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