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#tenofovir disoproxil fumarate

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FDA Approves Three New, Cheaper Combination ARV Tablets
Tenofovir Disoproxil Fumarate 101
Chart of Approved and Experimental HIV Medications

Switching to New Tenofovir Tied to Improved Bone Health in Older People With HIV

Participants entered the study taking tenofovir disoproxil fumarate, and some were switched to a regimen including tenofovir alafenamide.

Biktarvy Maintains High Efficacy for Three Years in Clinical Trials

The integrase inhibitor–based HIV regimen was compared with dolutegravir-based regimens.

Switching to Descovy for PrEP Improves Kidney and Bone Biomarkers

However, serious kidney problems and bone fractures were rare among people taking either Descovy or Truvada for HIV prevention.

Switching to New Tenofovir Linked to Rise in BMI and Cardiovascular Risk

This finding from a study of people switching from TDF to TAF for HIV treatment may also have implications for those on PrEP.

Switching Back to Older Tenofovir Improves Lipid Levels

The newer tenofovir formulation can raise cholesterol and triglyceride levels, but these changes are reversible.

The International AIDS Society Conference’s Most Vital Findings

A roundup of POZ’s reporting on studies presented at the Mexico City conference about HIV treatment, vaccines, PrEP and other concerns.

Only Subnormal Kidney Function May Get Boost From Switch to New Tenofovir

Swiss researchers analyzed shifts in kidney function among those switching from the old form of the HIV medication to the new one.
Tivicay

Tivicay Plus Truvada or Descovy Is as Effective as Atripla at Treating HIV

However, Tivicay plus Descovy was associated with greater weight gain, especially among women.

Many Heavily Treated People With HIV Do Not Need NRTIs

Long-term salvage therapy without NRTIs suppressed HIV in nearly 80% of those who remained in care.
Descovy, which contains TAF, the updated version of tenofovir, along with emtricitabine.

Analysis Backs New Tenofovir’s Kidney Safety Over Old Version

Researchers compared data on more than 9,000 people with HIV who took either version of tenofovir.

AIDS Activists File Antitrust Lawsuit Against HIV Drug Manufacturers

Pharma giants made agreements to keep prices high and block competition for generics, the civil lawsuit alleges.

Gilead to Donate Up to 2.4M Bottles of HIV Prevention Pills Each Year in the U.S.

This will provide free PrEP to as many as 200,000 uninsured Americans until 2030.

Generic PrEP to Arrive in September 2020, but Will Big Savings Follow?

Only one company will sell a version of the HIV prevention pill Truvada. When others go to market, prices will likely drop further.

Lawsuit Alleges Safer Version of HIV Med Tenofovir Withheld

Tenofovir disoproxil fumarate is found in Truvada, Viread, Atripla, Complera and Stribild.
Pre-Exposure Prophylaxis (PrEP)

CDC Has Patents on PrEP, Advocates Find

Activists want future and retroactive royalties to pay for a national PrEP program.

FDA OKs Delstrigo and Pifeltro

Delstrigo (doravirine/lamivudine/tenofovir disoproxil fumarate) includes Pifeltro (doravirine) in a three-drug single-tablet regimen.
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