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Participants entered the study taking tenofovir disoproxil fumarate, and some were switched to a regimen including tenofovir alafenamide.
The integrase inhibitor–based HIV regimen was compared with dolutegravir-based regimens.
However, serious kidney problems and bone fractures were rare among people taking either Descovy or Truvada for HIV prevention.
This finding from a study of people switching from TDF to TAF for HIV treatment may also have implications for those on PrEP.
The newer tenofovir formulation can raise cholesterol and triglyceride levels, but these changes are reversible.
A roundup of POZ’s reporting on studies presented at the Mexico City conference about HIV treatment, vaccines, PrEP and other concerns.
Swiss researchers analyzed shifts in kidney function among those switching from the old form of the HIV medication to the new one.
However, Tivicay plus Descovy was associated with greater weight gain, especially among women.
Long-term salvage therapy without NRTIs suppressed HIV in nearly 80% of those who remained in care.
Researchers compared data on more than 9,000 people with HIV who took either version of tenofovir.
Pharma giants made agreements to keep prices high and block competition for generics, the civil lawsuit alleges.
This will provide free PrEP to as many as 200,000 uninsured Americans until 2030.
Only one company will sell a version of the HIV prevention pill Truvada. When others go to market, prices will likely drop further.
Tenofovir disoproxil fumarate is found in Truvada, Viread, Atripla, Complera and Stribild.
Activists want future and retroactive royalties to pay for a national PrEP program.
Delstrigo (doravirine/lamivudine/tenofovir disoproxil fumarate) includes Pifeltro (doravirine) in a three-drug single-tablet regimen.
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