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This finding did not vary based on the dose of the nucleoside reverse transcriptase translocation inhibitor, formerly called MK-8591.
Research in human cells and mice found the antiretroviral suppressed harmful chronic inflammation linked to age-related disorders.
An OK would add an indication for the use of these HIV medications among those switching from stable regimens.
Delstrigo (doravirine/lamivudine/tenofovir disoproxil fumarate) includes Pifeltro (doravirine) in a three-drug single-tablet regimen.
Gilead has based its entire HIV drug portfolio on updating tenofovir, ostensibly to make it safer for bones and kidneys.
According to 48-week data from a recent study, Delstrigo posted good marks against other HIV treatments.
Compared with a regimen based on Prezista, doravirine was better for blood lipids, including cholesterol and triglycerides.
The new drug application is for doravirine as both an individual tablet and part of a combination tablet.
The new single-tablet NNRTI regimen was less likely than Atripla to cause neurological symptoms.
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