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Increases in syphilis have been driven by new cases in men who have sex with men, an estimated half of whom have HIV.
An analysis of people with syphilis in British Columbia found people with HIV were more likely to have a case affecting the eyes.
In the past 18 months, 42 people who use drugs tested HIV positive in Multnomah County, which includes Portland.
A quarter of study participants accounted for three-quarters of newly diagnosed cases of chlamydia, gonorrhea and syphilis.
New HIV cases in the city remain higher than those in Los Angeles County and the state.
The Conference on Retroviruses and Opportunistic Infections in Seattle saw many important studies that are advancing the fight against HIV.
The diagnosis rate fell by 50 percent in just two years among gay and bi men who attended sexual clinics at least twice in one year.
This finding follows a recent study indicating that syphilis is on the rise among heterosexual people who inject drugs.
Although the highest syphilis rates are in gay and bi men, the STI is also rising quickly among heterosexuals.
Researchers have developed estimates of the statewide populations of men who have sex with men in order to conduct more granular analyses.
But gay men living with untreated HIV did see higher viral loads if they also had a sexually transmitted infection, says a new study.
Outpacing the recent rise in all syphilis cases, congenital cases are at their highest rate in a generation.
Meanwhile, new analyses of gonorrhea have raised concern at the CDC about emerging drug resistance.
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