#CD4

A large analysis of Austrian people living with HIV suggests that high CD4 counts are no protection against heart disease.

One new approach protects CD4 cells against HIV entry, while another snips out viral genes in infected cells.

Markers of immune activation rose, but only temporarily, around the transition to menopause.

Cirrhosis severity and CD4 cell counts were linked to a greater chance of developing liver cancer.

The updates include new information on optimizing therapy, dealing with virological failure and managing opportunistic infections.

Monitoring viral load and CD4 count can show how well treatment is working.

Larger studies suggest people living with HIV might have a modestly higher risk of severe COVID-19, but much remains to be learned.

My most recent labs revealed a record high CD4 count. Could isolation due to COVID-19 concerns be the culprit?

A discussion led by POZ founder Sean Strub about the early days of AIDS research.

HIV itself doesn’t raise the risk of getting the new virus, but some HIV-positive people are prone to severe illness.

But even starting antiretrovirals with a high CD4 count doesn’t close the wide gap in years lived without major health problems.

They’re the 2019 recipients of amfAR’s Mathilde Krim Fellowship in Basic Biomedical Research.

Of particular concern is the considerable proportion of HIV-positive women not getting viral load and CD4 tests often enough.

Expanded access study confirms the long-acting monoclonal antibody works well in people with extensive prior treatment.