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#HIVR4P 2021

New Vaccine Approaches Show Early Promise for HIV

Two experimental vaccine approaches, using mRNA protein delivery and germline targeting, are in the early stages of development.

Lenacapavir Shows Promise for Long-Acting HIV Treatment and Prevention

A single dose of the HIV capsid inhibitor reduced viral load in highly treatment-experienced people.

Rectal Lube May Need to Be Supercharged Before It’s Feasible

Early studies of dapivirine lubricant for anal sex indicate how far the field has come—and how far it still has to go.

HIV Protection, Birth Control Levels Vary in Studies of Vaginal Rings

To date, no head-to-head trial has compared the prevention methods.

Long-Acting Cabotegravir Is an Effective PrEP Option for Women

Cabotegravir injections and daily Truvada are both highly effective, but some people may find it easier to use the long-acting regimen.

Broadly Neutralizing Antibodies Cut HIV Infections, but Most Strains Are Unaffected

The new prevention approach shows promise, but it isn’t heading to the clinic anytime soon.

Islatravir Shows Promise for Once-Monthly Oral PrEP

Monthly islatravir pills are just one of the long-acting options in the HIV prevention pipeline.

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