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In theory, starting antiretrovirals quiets the immune system, leading more immune cells to become part of the inactive reservoir.
This finding from early laboratory research may aid in the quest for cure therapies.
A guest blog post by Andrew Ngo, age 18.
After almost a decade on antiretroviral therapy, half of study participants still had HIV in immune cells in their brain and spinal fluid.
Any HIV cure on the horizon will have to tackle macrophage immune cells as well as CD4 T Cells, a study indicates.
A new, more accurate HIV reservoir test is a big advance for cure research.
The amfAR funding goes to scientists using nanotechnology and protein “fingerprinting.”
An all-female panel of amfAR-funded HIV scientists share insights on sex differences in the HIV reservoir, gender in research and more.
The Conference on Retroviruses and Opportunistic Infections in Seattle saw many important studies that are advancing the fight against HIV.
Samuel Weissman won second place at the 2019 Regeneron Science Talent Search. Next, he wants to help cure HIV.
In a study of people with a low but detectable viral load despite adherence to treatment, infected cells were apparently cloning themselves.
Previous studies found Tivicay monotherapy was subpar, but this trial switched people to the drug who had started combo treatment early.
HIV cure research has principally focused on latently infected CD4 cells as the backbone of the viral reservoir.
Experimental agent shrinks HIV reservoir, but fails to delay viral rebound.
The inability to precisely assess reservoir size has greatly hindered efforts to determine the effects of experimental cure therapies.
Researchers examined differences in the strength of a gene called nef.
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