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The amount of virus hidden in reservoir cells was not tied to inflammation in a small study, but the cells’ production of new RNA was.
Assessing the viral reservoir is traditionally akin to searching for needles in myriad haystacks.
The BEAT-HIV Martin Delaney Collaboratory has issued the first comprehensive set of recommendations for such assessments.
A specific protein on the surface of immune cells taken from the tonsils indicated they were reservoir cells.
Research indicates that there are numerous differences in how HIV behaves in women versus men.
Researchers found that during the earliest phases of infection, the reservoir is quite susceptible to antiretroviral treatment.
The man was treated for lymphoma with a stem cell transplant using immune cells that had an uncommon, naturally occurring resistance to HIV.
In theory, starting antiretrovirals quiets the immune system, leading more immune cells to become part of the inactive reservoir.
They’re the 2019 recipients of amfAR’s Mathilde Krim Fellowship in Basic Biomedical Research.
This finding from early laboratory research may aid in the quest for cure therapies.
A guest blog post by Andrew Ngo, age 18.
After almost a decade on antiretroviral therapy, half of study participants still had HIV in immune cells in their brain and spinal fluid.
Any HIV cure on the horizon will have to tackle macrophage immune cells as well as CD4 T Cells, a study indicates.
A new, more accurate HIV reservoir test is a big advance for cure research.
The amfAR funding goes to scientists using nanotechnology and protein “fingerprinting.”
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