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The approval makes this the first single-pill regimen containing dolutegravir available in a water-dispersible formulation.
Compared to other common HIV treatments, dolutegravir-based regimens maintained viral suppression even without perfect adherence.
People who switched to such a regimen gained up to 10 pounds in nine months.
The small single-site study will need to be replicated in a larger group of adolescents.
Many participants on two-drug regimens had more treatment under their belt and more chronic conditions.
Study results confirm that dolutegravir is a safe and effective treatment for pregnant women with HIV.
People whose viral load rebounds on Tivicay may not need to switch medications.
The findings highlight an ongoing need for better integration of HIV care with sexual and reproductive health care.
These two integrase inhibitors are associated with high blood sugar and diabetes.
ViiV’s two-drug Dovato also boasted a high genetic barrier to the development of viral resistance.
Researchers are surprised and concerned that a strain of HIV that is so broadly resistant to treatment even has the capacity to transmit.
A man with HIV is in long-term viral remission after intensified treatment.
Previously, kids weighing 44 to 88 pounds had to take lower doses—which are less available worldwide—and do so more than once a day.
HIV-positive individuals who have cycled through numerous antiretrovirals have poorer immune system function and more health problems.
A 2018 report had suggested that HIV-positive women’s use of the drug at conception increased the risk of the rare birth defects.
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